Publications
Working Group Cellular Protein Homeostasis
Kurpa O and Amponsah PS (2025). How do genome abnormalities impact mitochondrial homeostasis? BIOspektrum 31, 23-25. doi: 10.1007/s12268-025-2372-5
Amponsah PS, and Storchova Z (2025). The proteostasis burden of aneuploidy. Biol Chem. 406, 331-343. doi: 10.1515/hsz-2024-0163
Amponsah PS, Bökenkamp J, Kurpa O, Lenhard S, Myronova A, Velazquez DOV, Hirschelmann C, Behrends C, Herrmann JM, Räschle M, and Storchova Z (2025). Aneuploidy-induced proteostasis disruption impairs mitochondrial functions and mediates aggregation of mitochondrial precursor proteins through SQSTM1/p62. Nat Commun 16, 5328. doi: 10.1038/s41467-025-60857-4
Zimmermann J, Lang L, Calabrese G, Laporte H, Amponsah PS, Michalk C, Sukmann T, Oestreicher J, Tursch A, Peker E, Owusu TNE, Weith M, Roma LP, Deponte M, Riemer J, Morgan B (2025). Tsa1 is the dominant peroxide scavenger and a source of H₂O₂-dependent GSSG production in yeast. Free Radic. Biol. Med. 226, 408-420. doi: 10.1016/j.freeradbiomed.2024.11.004
Morgan B, Van Laer K, Owusu TN, Ezerina D, Pastor-Flores D, Amponsah PS, Tursch A, Dick TP (2016). Real-time monitoring of basal H₂O₂ levels with peroxiredoxin-based probes. Nat. Chem. Biol. 12, 437-443. doi: 10.1038/nchembio.2067
Fan P, Liu L, Yin Y, Zhao Z, Zhang Y, Amponsah PS, Xiao X, Bauer N, Abukiwan A, Nwaeburu CC, Gladkich J, Gao C, Schemmer P, Gross W, Herr I (2016). MicroRNA-101-3p reverses gemcitabine resistance by inhibition of ribonucleotide reductase M1 in pancreatic cancer. Cancer Lett. 373, 130-137. doi: 10.1016/j.canlet.2016.01.038
Amponsah PS (2016). Cellular redox - living chemistry. Science in School 36: 15-17. scienceinschool.org/article/2016/cellular-redox-living-chemistry/