Publikationen
Arbeitsgruppe Zelluläre Proteinhomöostase
2025
Kurpa O and Amponsah PS (2025). How do genome abnormalities impact mitochondrial homeostasis? BIOspektrum 31, 23-25. doi: 10.1007/s12268-025-2372-5
Amponsah PS, and Storchova Z (2025). The proteostasis burden of aneuploidy. Biol Chem. 406, 331-343. doi: 10.1515/hsz-2024-0163
Amponsah PS, Bökenkamp J, Kurpa O, Lenhard S, Myronova A, Velazquez DOV, Hirschelmann C, Behrends C, Herrmann JM, Räschle M, and Storchova Z (2025). Aneuploidy-induced proteostasis disruption impairs mitochondrial functions and mediates aggregation of mitochondrial precursor proteins through SQSTM1/p62. Nat Commun 16, 5328. doi: 10.1038/s41467-025-60857-4
Zimmermann J, Lang L, Calabrese G, Laporte H, Amponsah PS, Michalk C, Sukmann T, Oestreicher J, Tursch A, Peker E, Owusu TNE, Weith M, Roma LP, Deponte M, Riemer J, Morgan B (2025). Tsa1 is the dominant peroxide scavenger and a source of H2O2-dependent GSSG production in yeast. Free Radic. Biol. Med. 226, 408-420. doi: 10.1016/j.freeradbiomed.2024.11.004
2022
Yahya G, Menges P, Amponsah PS, Ngandiri DA, Schulz D, Wallek A, Kulak N, Mann M, Cramer P, Savage V, Räschle M, and Storchova Z (2022). Sublinear scaling of the cellular proteome with ploidy. Nat Commun: 13, 6182. doi: 10.1038/s41467-022-33904-7
2021
Amponsah PS, Yahya G, Zimmermann J, Mai M, Mergel S, Mühlhaus T, Storchova Z, and Morgan B (2021). Peroxiredoxins couple metabolism and cell division in an ultradian cycle.
Nat Chem Biol 17, 477–484. doi: 10.1038/s41589-020-00728-9
2019
Calabrese G, Peker E, Amponsah PS, Hoehne MN, Riemer T, Mai M, Deponte M, Morgan B, Riemer J (2019). Hyperoxidation of mitochondrial peroxiredoxin limits H2O2-induced cell death in yeast. EMBO 38, e101552. doi: 10.15252/embj.2019101552
2017
Amponsah PS, Fan P, Bauer N, Zhao Z, Gladkich J, Fellenberg J, Herr I (2017). microRNA-210 overexpression inhibits tumor growth and potentially reverses gemcitabine resistance in pancreatic cancer. Cancer Lett. 388, 107-117. doi: 10.1016/j.canlet.2016.11.035
2016
Morgan B, Van Laer K, Owusu TN, Ezerina D, Pastor-Flores D, Amponsah PS, Tursch A, Dick TP (2016). Real-time monitoring of basal H2O2 levels with peroxiredoxin-based probes. Nat. Chem. Biol. 12, 437-443. doi: 10.1038/nchembio.2067
Fan P, Liu L, Yin Y, Zhao Z, Zhang Y, Amponsah PS, Xiao X, Bauer N, Abukiwan A, Nwaeburu CC, Gladkich J, Gao C, Schemmer P, Gross W, Herr I (2016). MicroRNA-101-3p reverses gemcitabine resistance by inhibition of ribonucleotide reductase M1 in pancreatic cancer. Cancer Lett. 373, 130-137. doi: 10.1016/j.canlet.2016.01.038
Amponsah PS (2016). Cellular redox – living chemistry. Science in School 36: 15-17. scienceinschool.org/article/2016/cellular-redox-living-chemistry/
