Division of Graduate program

2018

  • Dürrbaum M, Kruse C, Nieken KJ, Habermann B, Storchová Z (2018) The deregulated microRNAome contributes to the cellular response to aneuploidy. BMC Genomics 19:197; doi.org/10.1186/s12864-018-4556-6.
  • Viganó C, von Schubert C, Ahrné E, Schmidt A, Lorber T, Bubendorf L, De Vetter JRF, Zaman GJR, Storchova Z, Nigg EA. Quantitative proteomic and phospho-proteomic comparison of human colon cancer DLD-1 cells differing in ploidy and chromosome stability. Mol Biol Cell. 2018 Mar 1. pii: mbc.E17-10-0577. doi: 10.1091/mbc.E17-10-0577. Epub ahead of print
  • Storchová Z.: Sphingolipid Turnover Turns Over the Fate of Aneuploid Cells. Trends Genet. 2018 Apr;34(4):255-256. doi: 10.1016/j.tig.2018.02.004. Epub 2018 Feb 21.

2017

Sheltzer JM, Ko J, Habibe Burgos NC, Chung E, Meehl CM, Passerini V, Storchová Z, Amon (2017) Single-chromosome aneuploidy commonly functions as a tumor suppressor, Cancer Cell, 31:240-255.

Libouban MAA, de Roos JADM, Uitdehaag JCM, Willemsen-Seegers N, Mainardi S, Dylus J, de Man J, Tops B, Meijerink JPP, Storchová Z, Buijsman RC, Medema RH, Zaman GJR. (2017) Stable aneuploid tumors cells are more sensitive to TTK inhibition than chromosomally unstable cell lines. Oncotarget. 8:38309-38325. doi: 10.18632/oncotarget.16213.

Domingues PH, Nanduri LS, Seget K, Venkateswaran SV, Agorku D, Viganó C, von Schubert C, Nigg EA, Swanton C, Sotillo R, Bosio A, Storchová Z, Hardt O. (2017) Cellular prion protein PRPC and ecto-5'-nucleotidase are markers of the cellular stress response to aneuploidy. Cancer Res. 77: 2914-2926. doi: 10.1158/0008-5472.CAN-16-3052.

 

2016

Storchová Z. (2016) Too much to differentiate: aneuploidy promotes proliferation and teratoma formation in embryonic stem cells. EMBO J.: e201695486.

McShane E, Sin C, Zauber H, Wells J, Donnelly N, Wang X, Hou Y, Chen W, Storchová Z, Marsh J, Valeriani A and Selbach M (2016) Kinetic Analysis of Protein Stability Reveals Age-Dependent Degradation. Cell 167:803-815, doi: 10.1016/j.cell.2016.09.015

Passerini V, Storchová Z. (2016) Too much to handle - how gaining chromosomes destabilizes the genome. Cell Cycle. 16:1-8.

Storchová Z, Kloosterman WP (2016) The genomic characteristics and cellular origin of chromothripsis, Curr Opin Cell Biol.; 40:106-13. doi: 10.1016/j.ceb.2016.03.003.

Passerini V, Ozeri-Galai E, de Pagter MS, Donnelly N, Schmalbrock S, Kloosterman WP, Kerem B, Storchová Z (2016) The presence of extra chromosomes leads to genomic instability, Nat Commun. 7:10754. doi: 10.1038/ncomms10754.

Lamm N, Ben-David U, Golan-Lev T, Storchová Z, Benvenisty Z, Kerem B (2016) Genomic instability in human pluripotent stem cells arises from replicative stress and chromosome condensation defects, Cell Stem Cell 18: 253-61. doi:10.1016/j.stem.2015.11.003.

Klionsky DJ et al (2016) Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy 12:1-222.

Dürrbaum M, Storchová Z (2015) Effects of aneuploidy on gene expression: implications for cancer, FEBS J. 283: 791-802; doi: 10.1111/febs.13591.

 

2015

Kuznetsova AY, Seget K, Moeller GK, de Pagter MS, de Roos JADM, Dürrbaum M, Kuffer C, Müller S, Zaman GJR, Kloosterman WP, Storchová Z (2015) Whole genome doubling promotes chromosomal instability, tolerance of mitotic errors and multidrug resistance, Cell Cycle 14: 2810-20.

Räschle M, Hansen RK, Smeenk G, Temu T, Hein MY, Nagaraj N, Oka Y, Long DT, Schmalbrock S, Walter JC, Storchová Z, Hofmann K, Bekker-Jensen S, Mailand N, Mann M (2015) Time-resolved proteomics of ICL repair reveals a SMC5/6 recruitment pathway, Science 348:1253671.

Donnelly N, Storchová Z (2015) Causes and consequences of protein folding stress in aneuploid cells, Cell Cycle, 14:4, 495-501.

Donnelly N, Storchová Z (2015) Aneuploidy and proteotoxic stress in cancer, Molecular & Cellular Oncology, 2: e976491.

 

2014

Donnelly N, Passerini V, Dürrbaum M, Stingele S, Storchová Z (2014) HSF1 deficiency and impaired HSP90-dependent protein folding are hallmarks of aneuploid human cells, EMBO Journal 33:2374-87.

Peplowska K, Wallek AU, Storchová Z (2014) Sgo1 Regulates both Condensin and Ipl1/Aurora B to Promote Chromosome Biorientation, PLoS Genet. 10: e1004411.

Storchová Z (2014) Ploidy changes and genome stability in yeast, Yeast 31:421-30. doi: 10.1002/yea.3037.

Dürrbaum M, Kuznetsova AY, Passerini V, Stingele S, Stoehr G, Storchová Z (2014) Unique features of the transcriptional response to model aneuploidy in human cells. BMC Genomics 2014, 15:139 - 52.

Donnelly N, Storchová Z (2014) Dynamic karyotype, dynamic proteome: Buffering the effects of aneuploidy. Biochim Biophys Acta.1843:473-81.

 

2013

Hahn M, Dambacher S, Dulev S, Kuznetsova AY, Eck S, Wörz S, Sadic D, Schulte M, Mallm J-P, Schermelleh L, Debs P, von Melchner H, Leonhardt H, Rohr K, Rippe K, Storchová Z, Schotta G (2013) Chromatin compaction by Suv4-20h2 is essential for cohesin recruitment to heterochromatin, Genes Dev. 27:859-72.

Kuffer C, Kuznetsova AY, Storchová Z (2013) Defective mitosis triggers the p53-dependent cell cycle arrest in human tetraploid cells, Chromosoma 122: 305-318.

Shaposhnikov D, Kuffer C, Storchová Z, Posern G (2013) Myocardin related transcription factors are required for coordinated cell cycle progression, Cell Cycle 12: 1762-72.

Stingele S, Stoehr G, Storchová Z (2013) Activation of autophagy in cells with abnormal karyotype, Autophagy 9:246-248.

 

2012

Stingele S, Stoehr G, Peplowska K, Cox J, Mann M, Storchová Z (2012) Global analysis of genome, transcriptome and proteome reveals cellular response to aneuploidy, Molecular Systems Biology 8: 608.

Stephan D, Sánchez-Soriano N, Loschek L, Gutmann S, Storchová Z, Prokop A, Grunwald Kadow I (2012) Drosophila Psidin is required for neurogenesis and axon targeting through two distinct molecular mechanisms, Journal of Neuroscience, J. Neurosci 32: 16080 – 16094.

Hüls D, Storchová Z, Niessing D (2012) ‎Posttranslational modifications regulate assembly of the early spindle-orientation complex in yeast, J. Biol. Chemistry 287: 16238-45.