PD Dr. David Scheuring
Contact:
Phytopathology
TU Kaiserslautern
Postfach 3049
D-67653 Kaiserslautern
Deutschland
Office:
Paul-Ehrlich-Straße
Bldg. 22; Room 104
Phone:
+49-631-205-2219
Email: scheurin[at]rptu.de
2023: Habilitation at the University of Kaiserslautern-Landau (RPTU)
since 2018: Group leader at the University of Kaiserslautern, Germany
2016 - 2018: Research associate, University of Kaiserslautern (Hahn group), Germany
2013 - 2016: Postdoc (DFG Fellowship), BOKU Vienna (Kleine-Vehn group), Austria
2011-2012: Postdoctoral Fellow, University of Heidelberg (Schumacher group), Germany
2007-2011: PhD at University of Heidelberg (Robinson group), Germany
2005/2006: ERASMUS fellowship at the University of Wolverhampton, UK
2001 - 2007: Studies of Biology at the University of Freiburg, Germany
Major Research Interest
Cells are the smallest units of life. Due to their sessile lifestyle, plants rely in particular on intracellular reactions to cope with changing environmental conditions. Thus, our research focus is to understand how plant cells behave during stress situations.
We aim to understand the cellular and molecular processes which allows for cell elongation and eventually plant growth. To this end, we use a combination of cell biological, genetic and biochemical approaches. Especially vesicle transport along actin filaments and morphological changes of cell organelles (e.g. the vacuole) are being investigated during abiotic and biotic (pathogens) stress. Deciphering these specific intracellular processes will allow to understand stress-induced plant growth regulation which might help to establish more robust plants withstanding future challenges.
Selected Publications
Müller J, König Y, Xhelilaj, K, Kaiser S, Müller T, Vielba-Fernández A, Gronnier J, Löfke C, Krebs M, Scheuring D (2025) Salicylic Acid inhibits V-ATPase activity and restricts cell elongation. Plant Phys 199: kiaf439 https://doi.org/10.1093/plphys/kiaf439
Müller J, Xhelilaj, K, Guichard M, Kaiser S, Grossmann G, Tenhaken R, Gronnier J, Scheuring D (2025) Salicylic acid-induced alkalinization of the apoplast requires TRANSMEMBRANE KINASE 1 and results in growth attenuation. bioRxiv 10.64898/2025.12.02.691772 https://doi.org/10.64898/2025.12.02.691772
Scheuring D, Minina EA, Krueger F, Krebs M, Schumacher K (2024) Light at the end of the tunnel: FRAP assays combined with super resolution microscopy confirm the presence of a tubular vacuole network in meristematic plant cells. Plant Cell, koae243 doi: 10.1093/plcell/koae243
Müller T, Bronkhorst J, Müller J, Safari N, Hahn M, Sprakel J, Scheuring, D (2024) Plant infection by the necrotrophic fungus Botrytis requires actin-dependent generation of high invasive turgor pressure. New Phytol; 244: 192–201 doi: 10.1111/nph.20025
Jeblick T, Leisen T, Steidele CE, Albert I, Mueller J, Kaiser S, Mahler F, Sommer F, Keller S, Hueckelhoven R, Hahn M, Scheuring, D (2023) Botrytis hypersensitive response inducing protein 1 triggers non-canonical PTI to induce plant cell death. Plant Phys. 191, 125-141
Valifard M, LeHir R, Müller J, Scheuring D, Neuhaus HE, Pommerrenig B (2021) The vacuolar fructose transporter SWEET17 is critical for Arabidopsis root development and drought tolerance. Plant Phys.187, 2716–2730
Niemeyer J, Scheuring D, Oestreicher J, Morgan B, Schroda M (2021) Real-time monitoring of subcellular H2O2 distribution in Chlamydomonas reinhardtii. Plant Cell. 33, 2935-2949
Kaiser Sand Scheuring D (2020) To lead or to follow: Contribution of the plant vacuole to cell growth. Front. Plant Sci. doi: 10.3389/fpls.2020.00553
Kaiser S, Eisa A, Kleine-Vehn J, Scheuring D (2019). NET4 modulates the compactness of vacuoles in Arabidopsis thaliana. Int. J. Mol Sci. 20, 4752, bioRxiv 714774
Scheuring D, Löfke C, Krüger F, Kittelmann M, Eisa A, Hughes L, Smith RS, Hawes C, Schumacher K and Kleine-Vehn J. (2016). Actin-dependent vacuolar occupancy of the cell determines auxin-induced growth repression. Proc Natl Acad Sci U S A. 113, 452-457
Scheuring D, Schöller M, Kleine-Vehn J and Löfke C (2015). Vacuolar staining methods in plant cells. Methods Mol Biol. 1242, 83-92
Löfke C*, Scheuring D*, Dünser K, Schöller M, Luschnig C and Kleine-Vehn J. (2015). Tricho- and atrichoblast cell files show distinct PIN2 auxin efflux carrier exploitations and are jointly required for defined auxin-dependent root organ growth. J Exp Bot. 66, 5103-5112
Löfke C, Dünser K, Scheuring D and Kleine-Vehn J. (2015). Auxin regulates SNARE-dependent vacuolar morphology restricting cell size. eLife 4, e05868
Viotti C, Krüger F, Krebs M, Neubert C, Fink F, Lupanga U, Scheuring D, Boutté Y, Frescatada-Rosa M, Wolfenstetter S, Sauer N, Hillmer S, Grebe M. and Schumacher K. (2013). The endoplasmic reticulum is the main membrane source for biogenesis of the lytic vacuole in Arabidopsis. Plant Cell. 25, 3434-49
Scheuring D*, Künzl F*, Viotti C, San Wan Yan M, Jiang L, Schellmann S., Robinson D.G. and Pimpl P. (2012). Ubiquitin initiates sorting of Golgi and plasma membrane proteins into the vacuolar degradation pathway. BMC Plant Biol. 12,164
Scheuring D*, Viotti C*, Krüger F, Künzl F, Sturm S, Bubeck J, Hillmer S, Frigerio L, Robinson D.G, Pimpl P and Schumacher K. (2011). Multivesicular bodies mature from the trans-Golgi network/early endosome in Arabidopsis. Plant Cell. 23, 3463-81
Niemes S, Labs M, Scheuring D, Krueger F, Langhans M, Jesenofsky B, Robinson DG and Pimpl P. (2010). Sorting of plant vacuolar proteins is initiated in the ER. Plant J. 62, 601-14
Bubeck J*, Scheuring D*, Hummel E, Langhans M, Viotti C, Foresti O, Denecke J, Banfield D.K and Robinson D. G. (2008). The syntaxins SYP31 and SYP81 control ER Golgi trafficking in the plant secretory pathway. Traffic 9, 1629-52
* Authors contributed equally