Bohnert M, Gatsogiannis C, Herrmann JM. 2024. The ATP-driven extractor ATAD1/Msp1 proof-reads protein translocation into mitochondria. Trends Cell Biol. 34, 698-699.
Pines O, Horwitz M, Herrmann JM. 2024. Privileged proteins with a second residence: dual targeting and conditional re-routing of mitochondrial proteins. FEBS J. 291, 1-15.
Kizmaz B, Nutz A, Egeler A, Herrmann JM. 2024. Protein insertion into the inner membrane of mitochondria: routes and mechanisms. FEBS Open Bio. 1-13.
Koch C, Lenhard S, Räschle M, Prescianotto-Baschong C, Spang A, Herrmann JM. 2024. The EF-SURF pathway uses ER-mitochondria contact sites for protein targeting to mitochondria. EMBO Rep. 25, 2071-2096.
Bertgen L, Bökenkamp J-E, Schneckmann T, Koch C, Räschle M, Storchová Z, Herrmann JM. 2024. Distinct types of intramitochondrial protein aggregates protect mitochondria against proteotoxic stress. Cell Rep. 43, 1-23.
Jung F, Rödl S, Herrmann JM, Mühlhaus T. 2024. Analysis and prediction of internal mitochondrial targeting signals. Methods Enzymol. 706, 263-283.
Herrmann JM, Lenhard S, Hansen KG. 2024. Import of mitochondrial precursor proteins into mitochondria of semi-intact yeast cells. Methods Enzymol. 706, 391-405.
2023
Lenhard S, Gerlich S, Khan A, Rödl S, Bökenkamp JE, Peker E, Zarges C, Faust J, Storchova Z, Räschle M, Riemer J, Herrmann JM. 2023 The Orf9b protein of SARS-CoV-2 modulates mitochondrial protein biogenesis. Journal of Cell Biology 222, 1-19.
Zannini F, Herrmann JM, Couturier J, Rouhier N. 2023. Oxidation of Arabidopsis thaliana COX19 Using the Combined Action of ERV1 and Glutathione. Antioxidants (Basel). 12, 1-14.
Rapaport D, Herrmann JM. 2023. Chasing the right tail: How the ER membrane complex recognizes its substrates. Journal of Cell Biology 222, 1-2.
Knöringer K, Groh C, Krämer L, Stein KC, Hansen KG, Zimmermann J, Morgan B, Herrmann JM, Frydman J, Boos F. 2023. The unfolded protein response of the endoplasmic reticulum supports mitochondrial biogenesis by buffering non-imported proteins. Mol Biol Cell. 34, 1-16.
Simakin P, Koch C, Herrmann JM. 2023. A modular cloning (MoClo) toolkit for reliable intracellular protein targeting in the yeast Saccharomyces cerevisiae. Microb Cell 10, 78-87.
Groh C, Haberkant P, Stein F, Filbeck S, Pfeffer S, Savitske MM, Boos F, Herrmann JM. 2023. Mitochondrial dysfunction rapidly modulates the abundance and thermal stability of cellular proteins. Life Sci Alliance 6, 1-16.
Krämer L, Dalheimer N, Räschle M, Storchova Z, Pielage J,, Boos F, Herrmann JM. 2023. MitoStores: chaperone-controlled protein granules store mitochondrial precursors in the cytosol. EMBO J 42, 1-18.
2022
Rödl S, den Brave F, Räschle M, Kizmaz B, Lenhard S, Groh C, Becker H, Zimmermann J, Morgan B, Richling E, Becker T, Herrmann JM. 2022. The metabolite-controlled ubiquitin conjugase Ubc8 promotes mitochondrial protein import. Life Sci Alliance 6, 1-16.
Güngör B, Flohr T, Garg SG, Herrmann JM. 2022. The ER membrane complex (EMC) can functionally replace the Oxa1 insertase in mitochondria. PLoS Biol 20, 1-18.
Bykov YS, Flohr T, Boos F, Zung N, Herrmann JM, Schuldiner M. 2022. Widespread use of unconventional targeting signals in mitochondrial ribosome proteins. EMBO J 41, 1-15.
2021
Duarte M, Ferreira C, Kaur Khandpur G, Flohr T, Zimmermann J, Castro H, Herrmann JM, Morgan B,Tomás AM. 2021. Leishmania type II dehydrogenase is essential for parasite viability irrespective of the presence of an active complex I. Proc. Natl. Acad. Sci. U.S.A 118, 1-11.
Groh C, Herrmann JM. 2021. Mitochondrial carriers set the epigenetic age. Nature Aging 1, 755-756.
Koch C, Schuldiner M, Herrmann JM. 2021. ER-SURF: Riding the Endoplasmatic Reticulum Surface to Mitochondria. Int. J. Mol. Sci. 22, 9655.
Schlagowski AM, Knöringer K, Morlot S, Sánchez Vicente A, Flohr T, Krämer L, Boos F, Khalid N, Ahmed S, Schramm J, Murschall LM, Haberkant P, Stein F, Riemer J, Westermann B, Braun RJ, Winklhofer KF, Charvin G, Herrmann JM. 2021. Increased levels of mitochondrial import factor Mia40 prevents the aggregation of poly! proteins in the cytosol. EMBO J 40, 1-23.
Schneider K, Zimmer D, Nielsen H, Herrmann JM, Mühlhaus T. 2021. iMLP a predictor for internal matrix targetin-like sequences in mitochondrial proteins. Biol. Chem. 402, 937-943.
Backes S, Bykov YS, Flohr T, Räschle M, Zhou J, Lenhard S, Krämer L, Mühlhaus T, Bibi C, Jann C, Smith JD, Steinmetz LM, Rapaport D, Storchova Z, Schuldiner M, Boos F, Herrmann JM. 2021. The chaperone-binding activity of the mitochondrial surface receptor Tom70 protects the cytosol against mitoprotein-induced stress. Cell Rep. 35, 1-17.
Laborenz J, Bykov YS, Knöringer K, Räschle M, Filker S, Prescianotto-Baschong C, Spang A, Tatsuta T, Langer T, Storchova Z, Schuldiner M, Herrmann JM. The ER-Protein Ema19 facilitates the degredation of nonimported mitochondrial precursor proteins. Mol Biol Cell. 32, 664-674.
Herrmann JM, Becker K, Dick TP. 2021. Dynamics of thiol-based redox switches: redox at its peak! Biol Chem. 402, 221-222.
Krämer L, Groh C, Herrmann JM. 2021. The Proteasom: friend and foe of mitochondrial biogenesis.FEBS Lett. 595, 1223-1238.
Itoh Y, Naschberger A, Mortezaei N, Herrmann JM, Amunts A. 2020. Analysis of translating mitoribosome reveals functional characteristics of translation in mitochondria of fungi. Nat. Commun. 11, 5187.
Boos F, Labbadia J, Herrmann JM. 2020. How the mitoprotein-induced stress response safeguards the cytosol: A unified view. Trends Cell Biol. 30, 241-254.
Friedl J, Knopp MR, Groh C, Paz E, Gould SB, Herrmann JM, Boos F. 2020. More than just a ticket canceller: The mitochondrial processing peptidase tailors complex precursor proteins at internal cleavage sites. Mol. Biol. Cell. 31, 2657-2668.
Bertgen L, Mühlhaus T, Herrmann JM. 2020. Clingy genes: Why were genes for ribosomal proteins retained in many mitochondrial genomes? Biochim Biophys Acta Bioenerg 1861, 148275.
Riemer J, Herrmann JM. 2020. Apoptosis inducing factor and mitochondrial NADH dehydrogenases: redox-controlled gear boxes to switch between mitochondrial biogenesis and cell death. Biol. Chem. 402, 298-297.
Zöller E, Laborenz J, Krämer L, Boos F, Räschle M, Alexander RT, Herrmann JM. 2020. The intermembrane space protein Mix23 is a novel stress-induced mitochondrial import factor. J. Biol. Chem. 295, 14686-14697.
Zimmermann J, Oestreicher J, Hess S, Herrmann JM, deponte M, Morgan B. 2020. One cysteine is enough: A monothiol Grx can functionally replace all cytosolic Trx and dithiol Grx. Redox. Biol. 36, 101598.
Bykov YS, Rapaport D, Herrmann JM, Schuldiner M. 2020. Cytosolic events in the biogenesis of mitochondrial proteins. Trends Biochem. Sci. 45, 650-667.
Ullah AKMS, Rumley AC, Peleh V, Fernandes D, Almomani EY, Berrini M, Lashhab R, Touret N, Alexander RT, Herrmann JM, Cordat E. 2020. SLC26A7 protein is a chloride/bicarbonate exchanger and its abundance is osmolarity- and pH-dependent in renal epithelial cells. Biochim Biophys Acta Biomembr 1862, 183238.
Saladi S, Boos F, Poglitsch M, Meyer H, Sommer F, Mühlhaus S, Schroda M, Schuldiner M, Madeo F, Herrmann JM. 2019. The NADH Dehydrogenase Nde1 Executes Cell Death after Integrating Signals from Metabolism and Proteostasis on the Mitochondrial Surface. Mol. Cell 77, 1–14.
2019
Beck-Sickinger A, Schwappach-Pignataro B, Herrmann JM, Buchner J. 2019. Open Access und die Zukunft wissenschaftlicher Veröffentlichungen. BioSpektrum 05/2019, 25, 245.
Bekeova C, Anderson-Pullinger L, Boye K, Boos F, Sharpadskaya Y, Herrmann JM, Seifert EL. 2019. Multiple mitochondrial thioesterases have distinct tissue and substrate specificity, and CoA regulation, suggesting unique functional roles. J. Biol. Chem. 294, 19034-19047.
Odendall F, Backes S, Tatsuta T, Weill U, Schuldiner M, Langer T, Herrmann JM, Rapaport D, Dimmer KS. 2019. The mitochondrial intermembrane space-facing proteins Mcp2 and Tgl2 are involved in yeast lipid metabolism. Mol. Biol. Cell 30, 2681-2694.
Laborenz J, Hansen KG, Prescianotto-Baschong C, Spang A, Herrmann JM. 2019. In vitro import experiments with semi-intact cells suggest a role of the Sec61 paralog Ssh1 in mitochondrial biogenesis. Biol. Chem. 400, 1229-1240.
Lill R, Langer T, Herrmann JM. 2019. Walter Neupert (1939-2019), a pioneer of mitochondrial biogenesis and morphology. EMBO J. 38, 1-2.
Hansen KG, Herrmann JM. 2019. Transport of Proteins into Mitochondria. Protein J. 38, 330-342.
Boos F, Krämer L, Groh C, Jung F, Haberkant P, Stein F, Wollweber F, Gackstatter A, Zöller E, van der Laan M, Savitski MM, Benes V, Herrmann JM. 2019. Mitochondrial protein-induced stress triggers a global adaptive transcriptional programme. Nat. Cell Biol. 21, 442-451.
Backes S, Garg SG, Becker L, Peleh V, Glockshuber R, Gould SB, Herrmann JM. 2019. Development of the mitochondrial intermembrane space disulfide relay represents a critical step in eukaryotic evolution. Mol. Biol. Evol. 36, 742-756.
Antunes D, Chowdhury A, Aich A, Saladi S, Harpaz N, Stahl M, Schuldiner M, Herrmann JM, Rehling P, Rapaport D. 2019. Overexpression of branched-chain amino acid aminotransferases rescues the growth defects of cells lacking the Barth syndrome-related gene TAZ1. J. Mol. Med 97, 269-279.
2018
Herrmann JM, Carvalho P, Hayer-Hartl M, Yoshihisa T. 2018. Life of proteins: from nascent chain to degradation. Nat. Struct. Mol. Biol. 25, 996-999.
Herrmann JM. 2018. A force-generating machine in the plant's power house: a pulling AAA ATPase motor drives protein translocation into chloroplasts. Plant Cell 30, 2646–2647.
Hansen KG, Aviram N, Laborenz J, Bibi C, Meyer M, Spang A, Schuldiner M, Herrmann JM. 2018. An ER surface retrieval pathway safeguards the import of mitochondrial membrane proteins in yeast. Science 361, 1118-1122.
Weill U, Yofe I, Sass E, Stynen B, Davidi D, Natarajan J, Ben-Menachem R, Avihou Z, Goldman O, Harpaz N, Chuartzman S, Kniazev K, Knoblach B, Laborenz J, Boos F, Kowarzyk J, Ben-Dor S, Zalckvar E, Herrmann JM, Rachubinski RA, Pines O, Rapaport D, Michnick SW, Levy ED, Schuldiner M. 2018. Genome-wide SWAp-Tag yeast libraries for proteome exploration. Nat. Methods 15, 617-622.
Zöller E, Todd Alexander R, Herrmann JM. 2018. Proteasomal degradation competes with Mia40-mediated import into mitochondria. BMC Biol. 16, 63.
Backes S, Hess S, Boos F, Woellhaf MW, Gödel S, Jung M, Mühlhaus T, Herrmann JM. 2018. Tom70 enhances mitochondrial preprotein import efficiency by binding to internal targeting sequences. J. Cell Biol. 217, 1369-1382.
Hansen KG, Boos F, Herrmann JM. 2018. Accessory signals in protein translocation. Aging, 10, 530-531.
Boos F, Mühlhaus T, Herrmann JM. 2018. Detection of Internal Matrix Targeting Signal-like Sequences (iMTS-Ls) in Mitochondrial Precursor Proteins Using the TargetP Prediction Tool. Bio-protocol Vol 8, Issue 17.
Carmona-Gutierrez D, Bauer MA, Zimmermann A, Aguilera A, Austriaco N, Ayscough K, Balzan R, Bar-Nun S, Barrientos A, Belenky P, Blondel M, Braun RJ, Breitenbach M, Burhans WC, Büttner S, Cavalieri D, Chang M, Cooper KF, Côrte-Real M, Costa V, Cullin C, Dawes I, Dengjel J, Dickman MB, Eisenberg T, Fahrenkrog B, Fasel N, Fröhlich KU, Gargouri A, Giannattasio S, Goffrini P, Gourlay CW, Grant CM, Greenwood MT, Guaragnella N, Heger T, Heinisch J, Herker E, Herrmann JM, Hofer S, Jiménez-Ruiz A, Jungwirth H, Kainz K, Kontoyiannis DP, Ludovico P, Manon S, Martegani E, Mazzoni C, Megeney LA, Meisinger C, Nielsen J, Nyström T, Osiewacz HD, Outeiro TF, Park HO, Pendl T, Petranovic D, Picot S, Polčic P, Powers T, Ramsdale M, Rinnerthaler M, Rockenfeller P, Ruckenstuhl C, Schaffrath R, Segovia M, Severin FF, Sharon A, Sigrist SJ, Sommer-Ruck C, Sousa MJ, Thevelein JM, Thevissen K, Titorenko V, Toledano MB, Tuite M, Vögtle FN, Westermann B, Winderickx J, Wissing S, Wölfl S, Zhang ZJ, Zhao RY, Zhou B, Galluzzi L, Kroemer G, Madeo F. 2018. Guidelines and recommendations on yeast cell death nomenclature. Microb. Cell 5, 4-31.
2017
Backes S, Herrmann JM. 2017. Protein Translocation into the Intermembrane Space and Matrix of Mitochondria: Mechanisms and Driving Forces.Front. Mol. Biosci. 4, 83.
Peleh, V, Zannini F, Backes S, Rouhier N, Herrmann JM. 2017. Erv1 of Arabidopsis thaliana can directly oxidize mitochondrial intermembrane space proteins in the absence of redox-active Mia40. BMC Biol. 15, 106.
Singhal RK, Kruse C, Heidler J, Strecker V, Zwicker K, Düsterwald L, Westermann B, Herrmann JM, Wittig I, Rapaport D. 2017. Coi1 is a novel assembly factor of the yeast complex III-complex IV supercomplex. Mol. Biol. 28, 2609-2622.
Ure ME, Heydari E, Pan W, Ramesh A, Rehman S, Morgan C, Pinsk M, Erickson R, Herrmann JM, Dimke H, Cordat E, Lemaire M, Walter M, Alexander RT. 2017. A variant in a cis-regulatory element enhances claudin-14 expression and is associated with pediatric-onset hypercalciuria and kidney stones. Hum. Mutat. 38, 649-657.
Ullrich P, Herrmann JM. 2017. Q&A with Johannes Herrmann, new President of German Society for Biochemistry and Molecular Biology (GBM). Elsevier Content.
2016
Peleh V, Cordat, E, Herrmann JM. 2016. Mia40 is a trans-site receptor that drives protein import into the mitochondrial intermembrane space by hydrophobic substrate binding. eLife 5:e16177.
Alfaiz AA, Müller V, Boutry-Kryza N, Ville D, Guex N, de Bellescize J, Rivier C, Labalme A, des Portes V, Edery P, Till M, Xenarios I, Sanlaville D, Herrmann JM, Lesca G, Reymond A. 2016. West syndrome caused by homozygous variant in the evolutionary conserved gene encoding the mitochondrial elongation factor GUF1. Eur. J. Hum. Genet. 24, 1001-1008.
Hansen KG, Schlagowski A, Herrmann JM. 2016. Escorted by chaperones: Sti1 helps to usher precursor proteins from the ribosome to mitochondria. FEBS J. 283, 3335-3337.
Woellhaf MW, Sommer F, Schroda M, Herrmann JM. 2016. Proteomic profiling of the mitochondrial ribosome identifies Atp25 as a composite mitochondrial precursor protein. Mol. Biol. Cell. 27, 3031-3039.
Ramesh A, Peleh V, Martinez-Caballero S, Wollweber F, Sommer F, van der Laan M, Schroda M, Alexander RT, Campo ML, Herrmann JM. 2016. A disulfide bond in the TIM23 complex is crucial for voltage gating and mitochondrial protein import. J. Cell Biol. 214, 417-431.
Boos F, Wollin M, Herrmann JM. 2016. Methionine on the rise: how mitochondria changed their codon usage. EMBO J. 35, 2066-2067.
Bode M, Woellhaf MW, Bohnert M, van der Laan M, Sommer F, Jung M, Zimmermann R, Schroda M, Herrmann JM. 2015. Redox-regulated dynamic interplay between Cox19 and the copper-binding protein Cox11 in the intermembrane space of mitochondria facilitates biogenesis of cytochrome c oxidase. Mol. Biol. Cell 26, 2385-2401.
van der Sluis EO, Bauerschmitt H, Becker T, Mielke T, Frauenfeld J, Berninghausen O, Neupert W, Herrmann JM, Beckmann R. 2015. Parallel structural evolution of mitochondrial ribosomes and OXPHOS complexes. Genome Biol. Evol. 7, 1235-1251.
Pfeffer S, Woellhaf MW, Herrmann JM, Förster F. 2015. Organization of the mitochondrial translation machinery studied in situ by cryoelecton tomography. Nat. Commun. 6, 6019.
Riemer J, Schwarzländer M, Conrad M, Herrmann JM. 2015. Thiol switches in mitochondria: operation and physiological relevance. Biol. Chem. 396, 465-482.
Herrmann JM, Becker K, Dick TP. 2015. Highlight: Dynamics of thiol-based redox switches. Biol. Chem. 396, 385-387.
Herrmann JM, Spang A. 2015. Intracellular parcel service: current issues in intracellular trafficking. Methods Mol. Biol. 1270, 1-12.
Kojer K, Peleh V, Calabrese G, Herrmann JM, Riemer J. 2015. Kinetic control by limiting glutaredoxin amounts enables thiol oxidation in the reducing mitochondrial IMS. Mol. Biol. Cell. 26, 195-204.
2014
Dalla Rosa I, Durigon R, Pearce SF, Rorbach J, Hirst EMA, Vidoni S, Reyes A, Brea-Calvo G, Minczuk M, Woellhaf MW, Herrmann JM, Huynen MA, Holt IJ, Spinazzola A. 2014. MPV17L2 is required for ribosome assembly in mitochondria. Nucleic Acids Res. 42, 8500-8515.
Woellhaf MW, Hansen KG, Garth C, Herrmann JM. 2014. Import of ribosomal proteins into yeast mitochondria. Biochem. Cell Biol. 92, 489-498.
Herrmann JM, Riemer J. 2014. Three approaches to one problem: Protein folding in the periplasm, the endoplasmic reticulum and the intermembrane space. Antioxid. Redox Signal. 21, 438-456.
Peleh V, Riemer J, Dancis A, Herrmann JM. 2014. Protein oxidation in the intermembrane space of mitochondria is substrate-specific rather than general. Microbial Cell 1, 81-93.
Longen S, Woellhaf MW, Petrungaro C, Riemer J, Herrmann JM. 2014. The Disulfide Relay of the Intermembrane Space Oxidizes the Ribosomal Subunit Mrp10 on Its Transit into the Mitochondrial Matrix. Dev. Cell 28, 30-42.
2013
Herrmann JM. 2013. The bacterial membrane insertase YidC is a functional monomer and binds ribosomes in a nascent chain-dependent manner.. J. Mol. Biol. 425, 4071-4073.
Weckbecker D, Herrmann JM. 2013. Methods to study the biogenesis of membrane proteins in yeast mitochondria. Methods Mol. Biol. 1033, 307-322.
Hoffmann C, Plocharski B, Haferkamp I, Leroch M, Ewald R, Bauwe H, Riemer J, Herrmann JM, Neuhaus HE. 2013. From endoplasmic reticulum to mitochondria: absence of the Arabidopsis ATP antiporter endoplasmic Reticulum Adenylate Transporter1 perturbs photorespiration.. Plant Cell 25, 2647-2660
Bode M, Longen S, Morgan B, Peleh V, Dick TP, Bihlmaier K, Herrmann JM. 2013. Inaccurately assembled cytochrome c oxidase can lead to oxidative stress-induced growth arrest. Antioxid. Redox Signal. 18, 1597-1612.
Fischer M, Horn S, Belkacemi A, Kojer K, Petrungaro C, Habich M, Ali M, Kuttner V, Bien M, Kauff F, Dengjel J, Herrmann JM, Riemer J. 2013. Protein import and oxidative folding in the mitochondrial intermembrane space of intact mammalian cells. Mol. Biol. Cell 24, 2160-2170.
Herrmann JM, Neupert W. 2013. Protein import into Mitochondria (Chapter). The Encyclopedia of Biological Chemistry 2nd edition, vol. 3, 632-636, Waltham, MA: Adademic Press
Herrmann JM. 2013. Oxidative Proteinfaltung: Der mitochondriale Intermembranraum ist voller Überraschungen. BIOspektrum 19, 247-249.
Funes S, Westerburg H, Jaimes-Miranda F, Woellhaf MW, Luis Aguilar-López J, Janßen L, Bonnefoy N, Kauff F, Herrmann JM. 2013. Partial suppression of Oxa1 mutants by mitochondria-targeted signal recognition particle reveals insights into the evolution of the co-translational insertion systems. FEBS J. 280, 904-915.
Herrmann JM, Woellhaf MW, Bonnefoy N. 2013. Control of protein synthesis in yeast mitochondria: the concept of translational activators. Biochim Biophys Acta 1822, 286-294.
2012
Weckbecker D, Longen S, Riemer J, Herrmann JM. 2012. Atp23 biogenesis reveals a chaperone-like folding activity of Mia40 in the IMS of mitochondria. EMBO J. 31, 4348-4358.
Keil M, Bareth B, Woellhaf MW, Peleh V, Prestele M, Rehling P, Herrmann JM. 2012. Oxa1-ribosome complexes coordinate the assembly of cytochrome c oxidase in mitochondria. J. Biol. Chem. 287, 34484-34493.
Hildenbeutel M, Theis M, Geier M, Haferkamp I, Neuhaus HE, Herrmann JM, Ott M. 2012. The membrane insertase Oxa1 is required for efficient import of carrier proteins into mitochondria. J. Mol. Biol. 423, 590-599.
Krueger V, Deckers M, Hildenbeutel M, Van der Laan M, Hellmers M, Drekers C, Preuss M, Herrmann JM, Rehling P, Wagner R, Meinecke M. 2012. The mitochondrial oxidase-assembly-protein1 (Oxa1) insertase forms a membrane pore in lipid bilayers. J. Biol. Chem. 287, 33314-33326.
Herrmann JM. 2011. MINOS is plus: a Mitofilin complex for mitochondrial membrane contacts. Dev. Cell 21, 599-600.
Gruschke S, Kehrein K, Römpler K, Gröne K, Israel L, Imhof A, Herrmann JM, Ott M. 2011. Cbp3-Cbp6 interacts with the yeast mitochondrial ribosomal tunnel exit and promotes cytochrome b synthesis and assembly. J. Cell Biol. 193, 1101-1114.
Riemer J, Fischer M, Herrmann JM. 2011. Oxidation-driven protein import into mitochondria: Insights and blind spots. Biochim Biophys Acta 1808, 981-989.
Funes S, Kauff F, van der Sluis EO, Ott M, Herrmann JM. 2011. Evolution of YidC/Oxa1/Alb3 insertases: three independent gene duplications followed by functional specialization in bacteria, mitochondria and chloroplasts. Biol. Chem. 392, 13-19.
Riemer J, Herrmann JM. 2011. Protein import into the intermembrane space of mitochondria. Methods in Protein Chemistry, Chapter 6, 95-112.
2010
Klöppel C, Michels C, Zimmer J, Herrmann JM, Riemer J. 2010. In yeast redistribution of Sod1 to the mitochondrial intermembrane space provides protection against respiration derived oxidative stress. Biochem. Biophys. Res. Commun. 403, 114-119.
Herrmann JM. 2010. Ups delivery to the intermembrane space of mitochondria: a novel affinity-driven protein import pathway. EMBO J. 29, 2859-2860.
Bohnert M, Rehling P, Guiard B, Herrmann JM, Pfanner N, van der Laan M. 2010. Cooperation of stop-transfer and conservative sorting mechanisms in mitochondrial protein transport. Curr. Biol. 20, 1227-1232.
Herrmann JM, Riemer J. 2010. Oxidation and reduction of cysteines in the intermembrane space of mitochondria: Multiple facets of redox-control. Antioxid. Redox Signal. 13, 1323-1326.
Bauerschmitt H, Mick DU, Deckers M, Vollmer C, Funes S, Kehrein K, Ott M, Rehling P, Herrmann JM. 2010. Ribosome-binding proteins Mdm38 and Mba1 display overlapping functions for regulation of mitochondrial translation. Mol. Biol. Cell 21, 1937-1944.
Gruschke S, Groene K, Heublein M, Hölz S, Israel L, Imhof A, Herrmann JM, Ott M. 2010. Proteins at the polypeptide tunnel exit of the yeast mitochondrial ribosome. J. Biol. Chem. 285, 19022-19028.
Bien M, Longen S, Wagener N, Chwalla I, Herrmann JM, Riemer J. 2010. Mitochondrial disulfide bond formation is driven by intersubunit electron transfer in Erv1 and proofread by glutathione. Mol. Cell 37, 516-528.
Ilkow CS, Weckbecker D, Cho WJ, Meier S, Beatch MD, Goping IS, Herrmann JM, Hobman TC. 2010. The rubella virus capsid protein inhibits mitochondrial import. J. Virol. 84, 119-130.
2009
Longen S, Bien M, Bihlmaier K, Kloeppel C, Kauff F, Hammermeister M, Westermann B, Herrmann JM, Riemer J. 2009. Systematic Analysis of the Twin Cx(9)C Protein Family. J. Mol. Biol. 393, 356-368.
Riemer J, Bulleid N, Herrmann JM. 2009. Disulfide formation in the ER and mitochondria: two solutions to a common process. Science 324, 1284-1287.
Prestele M, Vogel F, Reichert AS, Herrmann JM, Ott M. 2009. Mrpl36 is important for generation of assembly competent proteins during mitochondrial translation. Mol. Biol. Cell 20, 2615-2625.
Herrmann JM. 2009. Putting a break on protein translocation: metabolic regulation of mitochondrial protein import. Mol. Microbiol. 72, 275-278.
Funes S, Hasona A, Bauerschmitt H, Grubbauer C, Kauff F, Collins R, Crowley PJ, Palmer SR, Brady LJ, Herrmann JM. 2009. Independent gene duplications of the YidC/Oxa/Alb3 family enabled a specialized cotranslational function. Proc. Natl. Acad. Sci. U.S.A. 106, 6656-6661.
Eckers E, Bien M, Stroobant V, Herrmann JM, Deponte M. 2009. Biochemical Characterization of Dithiol Glutaredoxin 8 from Saccharomyces cerevisiae: The Catalytic Redox Mechanism Redux (dagger). Biochemistry 48, 1410-1413.
Herrmann JM, Kauff F and Neuhaus HE. 2009. Thiol oxidation in bacteria, mitochondria and chloroplasts: Common principles but three unrelated machineries? Biochim Biophys Acta 1793, 71-77.
2008
Herrmann JM, Spang A. 2008. Freight Management in the Cell: Current Aspects of Intracellular Membrane Trafficking. Methods Mol. Biol. 457, 3-12.
Bihlmaier K, Bien M, Herrmann JM. 2008. In Vitro Import of Proteins into Isolated Mitochondria. Methods Mol. Biol. 457, 85-94.
Bauerschmitt H, Funes S, Herrmann JM. 2008. Synthesis and Sorting of Mitochondrial Translation Products Methods Mol. Biol. 457, 95-112.
Mesecke N, Bihlmaier K, Grumbt B, Longen S, Terziyska N, Hell K, Herrmann JM. 2008. The zinc-binding protein Hot13 promotes oxidation of the mitochondrial import receptor Mia40. EMBO Rep. 9, 1107-1113.
Hildenbeutel M, Habib SJ, Herrmann JM, Rapaport D. 2008. New insights into the mechanism of precursor protein insertion into the mitochondrial membranes. Int Rev Cell Mol Biol 268, 147-190.
Mesecke N, Spang A, Deponte M, Herrmann JM. 2008. A Novel Group of Glutaredoxins in the cis-Golgi Critical for Oxidative Stress Resistance. Mol. Biol. Cell 19, 2673-2680.
Bauerschmitt H, Funes S, Herrmann JM. 2008. The Membrane-bound GTPase Guf1 Promotes Mitochondrial Protein Synthesis under Suboptimal Conditions. J. Biol. Chem. 283, 17139-17146.
Mesecke N, Mittler S, Eckers E, Herrmann JM, Deponte M. 2008. Two novel monothiol glutaredoxins from Saccharomyces cerevisiae provide further insight into iron-sulfur cluster binding, oligomerization, and enzymatic activity of glutaredoxins. Biochemistry 247, 1452-1463.
Bihlmaier K, Mesecke N, Kloeppel C, Herrmann JM. 2008. The disulfide relay of the intermembrane space of mitochondria: an oxygen-sensing system? Ann. N. Y. Acad. Sci. 1147:293-302.
2007
Bihlmaier K, Mesecke N, Terziyska N, Bien M, Hell K, Herrmann JM. 2007. The disulfide relay system of mitochondria is connected to the respiratory chain. J. Cell Biol. 179, 389-395.
van Bloois E, Koningstein G, Bauerschmitt H, Herrmann JM, Luirink J. 2007. Saccharomyces cerevisiae Cox18 complements the essential Sec-independent function of Escherichia coli YidC. FEBS J. 274, 5704-5713.
Funes S, Herrmann JM. 2007. Analysis of mitochondrial protein synthesis in yeast. In: Methods in Molecular Biology. Mitochondria, Practical Protocols, Volume 372, eds. Leister D, Herrmann JM. Methods Mol. Biol. 372, 255-263.
Leister D, Herrmann JM (editors). 2007. Methods in Molecular Biology. Mitochondria, Practical Protocols Methods Mol. Biol. 372.
Herrmann JM, Bihlmaier K, Mesecke N. 2007. The Role of the Mia40-Erv1 Disulfide Relay System in Import and Folding of Proteins of the Intermembrane Space of Mitochondria. In: The Enzymes: Molecular Machines Involved in Protein Transport across Cellular Membranes 25, eds. Koehler C, Dalbey R. Academic Press, 345-366.
Herrmann JM, Köhl R. 2007. Catch me if you can! Oxidative protein trapping in the intermembrane space of mitochondria. J. Cell Biol. 176, 559-563.
Martinez-Caballero S, Grigoriev SM, Herrmann JM, Campo ML, Kinnally KW. 2007. Tim17p regulates the twin-pore structure and voltage gating of the mitochondrial protein import complex TIM23. J. Biol. Chem. 282, 3584-3593.
Terziyska N, Grumbt B, Bien M, Neupert W, Herrmann JM, Hell K. 2007. The sulfhydryl oxidase Erv1 is a substrate of the Mia40-dependent protein translocation pathway. FEBS Lett. 581, 1098-1102.
Khalimonchuk O, Ott M, Funes S, Ostermann K, Rödel G, Herrmann JM. 2006. Sequential processing of a mitochondrial tandem protein: Insights into the protein import in Schizosaccharomyces pombe. Eukaryotic Cell 5, 997-1006.
Ott M, Prestele M, Bauerschmitt H, Funes S, Bonnefoy N, Herrmann JM. 2006. Mba1, a membrane-associated ribosome receptor in mitochondria. EMBO J. 25, 1603-1610.
2005
Meier S, Neupert W, Herrmann JM. 2005. Proline residues of transmembrane domains determine the sorting of inner membrane proteins in mitochondria. J. Cell Biol. 170, 881-888.
Mesecke N, Terziyska N, Kozany C, Baumann F, Neupert W, Hell K, Herrmann JM. 2005. A disulfide relay system in the intermembrane space of mitochondria that mediates protein import. Cell 121, 1059-1069.
Herrmann JM, Hell K. 2005. Chopped, trapped or tacked - Protein translocation into the intermembrane space of mitochondria. Trends Biochem. Sci. 30, 205-212.
Herrmann JM. 2005. Proteintransportmaschinen in Mitochondrien - Ein Mosaik aus Proteinkomplexen unterschiedlicher phylogenetischer Abstammung. Naturwissenschaftliche Rundschau 10, 525-530.
Bloois EV, Nagamori S, Koningstein G, Ullers RS, Preuss M, Oudega B, Harms N, Kaback HR, Herrmann JM, Luirink J. 2005. The Sec-independent function of E. coli YidC is evolutionary conserved and essential. J. Biol. Chem. 280, 12996-13003.
Preuss M, Ott M, Funes S, Luirink J, Herrmann JM. 2005. Evolution of mitochondrial Oxa proteins from bacterial YidC: Inherited and acquired functions of a conserved protein insertion machinery. J. Biol. Chem. 280, 13004-13011
Herrmann JM, Funes S. 2005. Biogenesis of cytochrome oxidase - sophisticated assembly lines in the mitochondrial inner membrane. Gene 354, 43-52
Meier S, Neupert W, Herrmann JM. 2005. Conserved N-terminal negative charges in the Tim17 subunit of the TIM23 translocase play a critical role in the import of preproteins into mitochondria. J. Biol. Chem. 280, 7777-7785.
Terziyska N, Lutz T, Kozany C, Mokranjac D, Mesecke N, Neupert W, Herrmann JM, Hell K. 2005. Mia40, a novel factor for protein import into the intermembrane space of mitochondria is able to bind metal ions. FEBS Lett. 579, 179-184.
Funes S, Gerdes L, Inaba M, Soll J, Herrmann JM. 2004. The Arabidopsis thaliana chloroplast inner envelope protein ARTEMIS is a functional member of the Alb3/Oxa1/YidC family of proteins. FEBS Lett. 569, 89-93.
Tzagoloff A, Barientos A, Neupert W, Herrmann JM. 2004. Atp10p assists assembly of Atp6p into the Fo unit of the yeast mitochondrial ATPase. J. Biol. Chem. 279, 19775-19780.
Funes S, Nargang FE, Neupert W, Herrmann JM. 2004. The Oxa2 protein of Neurospora crassa plays a critical role in the biogenesis of cytochrome oxidase and defines a ubiquitous subbranch of the Oxa1/YidC/Alb3 protein family. Mol. Biol. Cell. 15, 1853-1861.
Herrmann JM, Bonnefoy N. 2004. Protein export across the inner membrane of mitochondria: The nature of translocated domains determines the dependence on the Oxa1 translocase. J. Biol. Chem. 279, 2507-2512.
2003
Szyrach G, Ott M, Bonnefoy N, Neupert W, Herrmann JM. 2003. Ribosome binding to the Oxa1 translocase facilitates cotranslational protein insertion in mitochondria. EMBO J. 22, 6448-6457.
Lutz T, Neupert W, Herrmann JM. 2003. Import of small Tim proteins into the mitochondrial intermembrane space. EMBO J. 22, 4400-4408.
Herrmann JM, Neupert W. 2003. Protein insertion into the inner membrane of mitochondria. IUBMB Life 55, 219-225.
Sandmann T, Herrmann JM, Dengjel J, Schwarz H, Spang A. 2003. Suppression of coatomer mutants by a new protein family with COPI and COPII binding motifs in S. cerevisiae. Mol. Biol. Cell 14, 3097-3113
Meier S, Herrmann JM. 2003. Quo vadis, Protein? Proteinsortierung in Mitochondrien. Bioforum 1-2/2003, 32-34.
Herrmann JM. 2003. Converting bacteria to organelles: evolution of mitochondrial protein sorting. Trends Microbiol. 11, 74-79.
2002
Duby G, Foury F, Ramazotti A, Herrmann JM, Lutz T. 2002. A non-essential function for yeast frataxin in iron-sulfur cluster assembly. Hum. Mol. Genet. 11, 2635-2643.
Baumann F, Neupert W, Herrmann JM. 2002. Insertion of bitopic membrane proteins into the inner membrane of mitochondria involves an export step from the matrix. J. Biol. Chem. 277, 21405-21413.
Nargang FE, Preuss M, Neupert W, Herrmann JM. 2002. The Oxa1 protein forms a homooligomeric complex and is an essential part of the mitochondrial export translocase in Neurospora crassa. J. Biol. Chem. 277, 12846-12853.
2001
Preuss M, Leonhard K, Neupert W, Herrmann JM. 2001. Mba1, a novel component of the mitochondrial protein export machinery of the yeast S. cerevisiae. J. Cell Biol. 153, 1035-1045.
Lutz T, Westermann B, Neupert W, Herrmann JM. 2001. The mitochondrial proteins Ssq1 and Jac1 are required for the assembly of iron sulfur clusters in mitochondria. J. Mol. Biol. 307, 815-825.
Spang A, Herrmann JM, Hamamoto S, Schekman R. 2001. The ADP ribosylation factor-nucleotide exchange factors Gea1p and Gea2p have overlapping, but not redundant functions in retrograde transport from the Golgi to the endoplasmic reticulum. Mol. Biol. Cell 12, 1035-1045.
Herrmann JM, Westermann B, Neupert W. 2001. Analysis of protein-protein interactions in mitochondria by co-immunoprecipitation and chemical cross-linking. Methods Cell Biol. 65, 217-230.
Westermann B, Herrmann JM, Neupert W. 2001. Analysis of mitochondrial translation products in vivo and in organello in yeast. Methods Cell Biol. 65, 429-438.
2000
Baumann F, Milisav E, Neupert W, Herrmann JM. 2000. Ecm10, a novel Hsp70 homolog in the mitochondrial matrix of the yeast Saccharomyces cerevisiae. FEBS Lett. 487, 307-312.
Berger T, Brigl M, Herrmann JM, Vielhauer V, Luckow B, Schlöndorff D, Kretzler M. 2000. The apoptosis mediator mDAP-3 is a novel member of a conserved family of mitochondrial proteins. J. Cell. Sci. 113, 3603-3612.
Herrmann JM, Neupert W. 2000. What fuels polypeptide translocation? An energetical view on mitochondrial protein sorting. Biochim Biophys Acta 1459, 331-338.
Marzioch M, Henthorn DC, Hermann JM, Wilson R, Thomas DY, Bergeron JJ, Solari RC, Rowley A. 1999. Erp1p and Erp2p, partners for Emp24p and Erv25p in a yeast p24 complex. Mol. Biol. Cell 10, 1923-1938.
Herrmann JM, Malkus P, Schekman R. 1999. Out of the ER - outfitters, escorts and guides. Trends Cell Biol. 9, 5-7.
1998
Kuehn MJ, Herrmann JM, Schekman R. 1998. COPII-cargo interactions direct protein sorting into ER-derived transport vesicles. Nature 391, 187-190.
Hell K, Herrmann JM, Pratje E, Neupert W, Stuart RA. 1998. Oxa1p, an essential component of the N-tail protein export machinery in mitochondria. Proc. Natl. Acad. Sci. U.S.A. 95, 2250-2255.
1997
Hell K, Herrmann JM, Pratje E, Neupert W, Stuart RA. 1997. Oxa1p mediates the export of the N- and C-termini of pCoxII from the mitochondrial matrix to the intermembrane space. FEBS Lett. 418, 367-370.
Herrmann JM, Neupert W, Stuart RA. 1997. Insertion into the mitochondrial inner membrane of a polytopic protein, the nuclear-encoded Oxa1p. EMBO J. 16, 2217-2226.
1996
Westermann, B, Gaume B, Herrmann JM, Neupert W, Schwarz E. 1996. Role of the mitochondrial DnaJ homolog, Mdj1p, as a chaperone for mitochondrially synthesized and imported proteins. Mol. Cell Biol. 16, 7063-7071.
Leonhardt K, Herrmann JM, Stuart SA, Mannhaupt G, Neupert W, Langer T. 1996. AAA proteases with catalytic sites on opposite membrane surfaces cooperate in the ATP-dependent degradation of inner membrane proteins in mitochondria. EMBO J. 15, 4218-4229.
1995
Herrmann JM, Koll H, Cook RA, Neupert W, Stuart RA. 1995. Topogenesis of cytochrome oxidase subunit II. Mechanisms of protein export from the mitochondrial matrix. J. Biol. Chem. 270, 27079-27068.
1994
Herrmann JM, Stuart RA, Craig EA, Neupert W. 1994. Mitochondrial heat shock protein 70, a molecular chaperone for proteins encoded by mitochondrial DNA. J. Cell Biol. 127, 893-902.
Herrmann JM, Fölsch H, Stuart RA, Neupert W. 1994. Isolation of yeast mitochondria and study of mitochondrial protein translation. In Cell Biology: A Laboratory Handbook, Volume 1 (Celis, D.E., ed) 538-544, Academic Press Inc., New York.
1992
Fehler F, Herrmann JM, Saalmüller A, Mettenleiter TM, Keil GM. 1992. Glycoprotein IV of bovine herpes virus 1-expressing cell line complements and rescues a conditionally lethal viral mutant. J. Virol. 66, 831-839.