List of publications

Michael Schroda (on Google scholar)

A. Original articles in peer reviewed Journals

69. Zimmer, D., Schneider, K., Sommer, F., Schroda, M., and Mühlhaus, T. (2018). Artificial intelligence understands peptide observability and assists with absolute protein quantification. Front Plant Sci, 9.

68. Kuken, A., Sommer, F., Yaneva-Roder, L., Mackinder, L.C.M., Hohne, M., Geimer, S., Jonikas, M.C., Schroda, M., Stitt, M., Nikoloski, Z., and Mettler-Altmann, T. (2018). Effects of microcompartmentation on flux distribution and metabolic pools in Chlamydomonas reinhardtii chloroplasts. eLife, 7.

67. Crozet, P., Navarro, F.J., Willmund, F., Mehrshahi, P., Bakowski, K., Lauersen, K.J., Perez-Perez, M.E., Auroy, P., Gorchs Rovira, A., Sauret-Gueto, S., Niemeyer, J., Spaniol, B., Theis, J., Trosch, R., Westrich, L.D., Vavitsas, K., Baier, T., Hubner, W., de Carpentier, F., Cassarini, M., Danon, A., Henri, J., Marchand, C.H., de Mia, M., Sarkissian, K., Baulcombe, D.C., Peltier, G., Crespo, J.L., Kruse, O., Jensen, P.E., Schroda, M., Smith, A.G., and Lemaire, S.D. (2018). Birth of a photosynthetic chassis: a MoClo toolkit enabling synthetic biology in the microalga Chlamydomonas reinhardtii. ACS synthetic biology, 7, 2074-2086.

66. Hammel, A., Zimmer, D., Sommer, F., Mühlhaus, T., and Schroda, M. (2018). Absolute Quantification of Major Photosynthetic Protein Complexes in Chlamydomonas reinhardtii Using Quantification Concatamers (QconCATs). Front Plant Sci 9, 1265.

65. Müller, N., Leroch, M., Schumacher, J., Zimmer, D., Konnel, A., Klug, K., Leisen, T., Scheuring, D., Sommer, F., Muhlhaus, T., Schroda, M., and Hahn, M. (2018). Investigations on VELVET regulatory mutants confirm the role of host tissue acidification and secretion of proteins in the pathogenesis of Botrytis cinerea. New Phytol., 219,1062-1074.

64. Rütgers, M., Muranaka, L.S., Schulz-Raffelt, M., Thoms, S., Schurig, J., Willmund, F., and Schroda, M. (2017). Not changes in membrane fluidity but proteotoxic stress triggers heat shock protein expression in Chlamydomonas reinhardtii.Plant Cell Environ 40, 2987-3001.

63. Rütgers, M., Muranaka, L.S., Muhlhaus, T., Sommer, F., Thoms, S., Schurig, J., Willmund, F., Schulz-Raffelt, M., Schroda, M. (2017) Substrates of the chloroplast small heat shock proteins 22E/F point to thermolability as a regulative switch for heat acclimation in Chlamydomonas reinhardtii. Plant Mol Biol 95, 579-591.

62.Schroda, M., Grossman, A. (2017) Christoph Beck (1941-2017): a Chlamydomonas biologist. Photosynth Res 134, 231-232.

61. Auerbach H, Kalienkova V, Schroda M, Schünemann V (2017) Mössbauer spectroscopy of the chloroplast-targeted DnaJ-like proteins CDJ3 and CDJ4. Hyperfine Interactions 238, 86.

60. Ramesh, A., Peleh, V., Martinez-Caballero, S., Wollweber, F., Sommer, F., van der Laan, M., Schroda, M., Alexander, R. T., Campo, M. L. and Herrmann, J. M. (2016) A disulfide bond in the TIM23 complex is crucial for voltage gating and mitochondrial protein import. J. Cell Biol. 214, 417-431.

59. Woellhaf, M. W., Sommer, F., Schroda, M. and Herrmann, J. M. (2016) Proteomic profiling of the mitochondrial ribosome identifies Atp25 as a composite mitochondrial precursor protein. Mol. Biol. Cell. 27, 3031-3039.

58. Mackinder, L.C., Meyer, M.T., Mettler-Altmann, T., Chen, V.K., Mitchell, M.C., Caspari, O., Freeman Rosenzweig, E.S., Pallesen, L., Reeves, G., Itakura, A., Roth, R., Sommer, F., Geimer, S., Muhlhaus, T., Schroda, M., Goodenough, U., Stitt, M., Griffiths, H., and Jonikas, M.C. (2016). A repeat protein links Rubisco to form the eukaryotic carbon-concentrating organelle. Proc. Natl. Acad. Sci. U. S. A. 113, 5958-5963.

57. Tadini, L., Pesaresi, P., Kleine, T., Rossi, F., Guljamow, A., Sommer, F., Muhlhaus, T., Schroda, M.,Masiero, S., Pribil, M., Rothbart, M., Hedtke, B., Grimm, B., and Leister, D. (2016). GUN1 controls accumulation of the plastid ribosomal protein S1 at the protein level and interacts with proteins involved in plastid protein homeostasis. Plant Physiol., 170, 1817-1830.

56. Takahashi, H., Schmollinger, S., Lee, J.H., Schroda, M., Rappaport, F., Wollman, F.A., and Vallon, O. (2016). PETO interacts with other effectors of cyclic electron flow in Chlamydomonas. Mol Plant., 9, 558-568.

56. Muranaka, L.S., Rütgers, M., Bujaldon, S., Heublein, A., Geimer, S., Wollman, F.A. and Schroda, M. (2016) TEF30 interacts with photosystem II monomers and is involved in the repair of photodamaged photosystem II in Chlamydomonas reinhardtii. Plant Physiol., 170, 821-840.

55. Barahimipour, R., Strenkert, D., Neupert, J., Schroda, M., Merchant, S.S. and Bock, R. (2015) Dissecting the contributions of GC content and codon usage to gene expression in the model alga Chlamydomonas reinhardtii. Plant J., 84, 704–717.

54. Bode, M., Woellhaf, M.W., Bohnert, M., van der Laan, M., Sommer, F., Jung, M., Zimmermann, R., Schroda, M. and Herrmann, J.M. (2015) Redox-regulated dynamic interplay between Cox19 and the copper-binding protein Cox11 in the intermembrane space of mitochondria facilitates biogenesis of cytochrome c oxidase. Mol. Biol. Cell, 26, 2385-2401.

53. Jung, B., Ludewig, F., Schulz, A., Meißner, G., Wöstefeld, N., Flügge, U.-I.,. Pommerrenig, B., Wirsching, P., Sauer, N., Koch, W., Sommer, F., Mühlhaus, T., Schroda, M., Cuin, T., Graus, T., Marten, I., Hedrich, R., Neuhaus, H.E. (2015) Identification of the transporter responsible for sucrose accumulation in sugar beet taproots. Nat. Plants, 1, 14001.

52. Hemme, D., Veyel, D., Mühlhaus, T., Sommer, F., Jüppner, J., Unger, A.-K., Sandmann, M., Fehrle, I., Schönfelder, S., Steup, M., Geimer, S., Kopka, J., Giavalisco, P., and Schroda, M. (2014) Systems-wide analysis of acclimation responses to long-term heat stress and recovery in the photosynthetic model organism Chlamydomonas reinhardtii. Plant Cell, 26, 4270-4297.

51. Sommer, F., Mühlhaus, T., Hemme, D., Veyel, D., and Schroda, M. (2014)Identification and validation of protein-protein interactions by combining co-immunoprecipitation, antigen competition, and stable isotope labeling. Methods Mol. Biol., 1188, 245-261.

50. Mettler, T., Muhlhaus, T., Hemme, D., Schottler, M.A., Rupprecht, J., Idoine, A., Veyel, D., Pal, S.K., Yaneva-Roder, L., Winck, F.V., Sommer, F., Vosloh, D., Seiwert, B., Erban, A., Burgos, A., Arvidsson, S., Schonfelder, S., Arnold, A., Gunther, M., Krause, U., Lohse, M., Kopka, J., Nikoloski, Z., Mueller-Roeber, B., Willmitzer, L., Bock, R., Schroda, M., and Stitt, M. (2014). Systems Analysis of the Response of Photosynthesis, Metabolism, and Growth to an Increase in Irradiance in the Photosynthetic Model Organism Chlamydomonas reinhardtii. Plant Cell, 26, 2310-2350.

49. Ramundo, S., Casero, D., Muhlhaus, T., Hemme, D., Sommer, F., Crevecoeur, M., Rahire, M., Schroda, M., Rusch, J., Goodenough, U., Pellegrini, M., Perez-Perez, M.E., Crespo, J.L., Schaad, O., Civic, N., and Rochaix, J.D. (2014). Conditional Depletion of the Chlamydomonas Chloroplast ClpP1 Protease Activates Nuclear Genes Involved in Autophagy and Plastid Protein Quality Control.Plant Cell, 26, 2201-2222.

48. Schmollinger, S., Muhlhaus, T., Boyle, N.R., Blaby, I.K., Casero, D., Mettler, T., Moseley, J.L., Kropat, J., Sommer, F., Strenkert, D., Hemme, D., Pellegrini, M., Grossman, A.R., Stitt, M., Schroda, M., and Merchant, S.S. (2014). Nitrogen-Sparing Mechanisms in Chlamydomonas Affect the Transcriptome, the Proteome, and Photosynthetic Metabolism.Plant Cell, 26, 1410-1435.

47. Veyel, D., Erban, A., Fehrle, I., Kopka, J., and Schroda, M. (2014). Rationales and approaches for studying metabolism in eukaryotic microalgae. Metabolites 4, 184-217.

46. Veyel, D., Sommer, F., Muranaka, L.S., Rütgers, M., Lemaire, S.D., and Schroda, M. (2014) In vitro characterization of bacterial and chloroplast HSP70 systems reveals an evolutionary optimization of the co-chaperones for their HSP70 partner. Biochem. J., 460, 13-24.

45. Lohse, M., Nagel, A., Herter, T., May, P., Schroda, M., Zrenner, R., Tohge, T., Fernie, A.R., Stitt, M., Usadel, B. (2014) Mercator: A fast and simple web server for genome scale functional annotation of plant sequence data. Plant Cell Environ.37, 1250-1258.

44. Schmollinger, S., Schulz-Raffelt, M., Strenkert, D., Veyel, D., Vallon, O., and Schroda, M. (2013) Dissecting the heat stress response in Chlamydomonas by pharmaceutical and RNAi approaches reveals conserved and novel aspects. Mol. Plant, 6, 1795-1813.

43. Strenkert, D., Schmollinger, S., and Schroda, M. (2013) Heat shock factor 1 counteracts epigenetic silencing of nuclear transgenes in Chlamydomonas reinhardtii. Nucleic Acids Res., 41, 5273-5289.

42. Schmollinger, S., Strenkert, D., Offeddu, V., Nordhues, A., Sommer, F. and Schroda, M. (2012) A protocol for the identification of protein-protein interactions based on 15N metabolic labeling, immunoprecipitation, quantitative mass spectrometry and affinity modulation.J. Vis. Exp.,67, 4083.

41. Nordhues, A., Schöttler, M.A., Unger, A.K., Geimer, S., Schönfelder, S., Schmollinger, S., Rütgers, M., Finazzi, G., Soppa, B., Sommer, F., Mühlhaus, T., Roach, T., Krieger-Liszkay, A.,Lokstein, H., Crespo, J.L., Schroda, M. (2012) Evidence for a role of VIPP1 in the structural organization of the photosynthetic apparatus in Chlamydomonas. Plant Cell, 24,637-659.

40. Strenkert, D., Schmollinger, S., and Schroda, M. (2011) Protocol: methodology for chromatin immunoprecipitation (ChIP) in Chlamydomonas reinhardtii. Plant Methods, 7, 35.

39. Mühlhaus, T., Weiss, J., Hemme, D., Sommer, F., and Schroda, M. (2011) Quantitative shotgun proteomics using a uniform 15N-labeled standard to monitor proteome dynamics in time course experiments reveals new insights into the heat stress response of Chlamydomonas reinhardtii. Mol. Cell. Proteomics, 10, M110 004739.

38. Strenkert, D., Schmollinger, S., Sommer, F., Schulz-Raffelt, M., and Schroda, M. (2011) Transcription factor dependent chromatin remodeling at heat shock and copper responsive promoters in Chlamydomonas reinhardtii. Plant Cell, 23, 2285-2301.

37. Schmollinger, S., Strenkert, D., and Schroda, M. (2010) An inducible artificial microRNA system for Chlamydomonas reinhardtii confirms a key role for heat shock factor 1 in regulating thermotolerance.Curr. Genet. 56, 383-389.

36. Dorn, K. V., Willmund, F., Schwarz, C., Henselmann, C., Pohl, T., Heß, B., Usadel, B., Friedrich, T., Nickelsen, J, and Schroda, M. (2010) Chloroplast DnaJ-like proteins 3 and 4 (CDJ3/4) from Chlamydomonas reinhardtii contain redox-active iron-sulfur clusters and interact with stromal HSP70B.Biochem. J. 427, 205-215.

35. Meinecke, L., Alawady, A., Willows, R., Schroda, M., Grimm, B., and Beck, C. F. (2010) Chlorophyll-deficient mutants of Chlamydomonas reinhardtii blocked in Magnesium Protoporphyrin IX Methyltransferase. Plant Mol. Biol. 72, 643-658.

34. Heide, H., Nordhues, A., Drepper, F., Nick, S., Schulz-Raffelt, M., Haehnel, W., and Schroda, M. (2009) Application of QUICK-X (quantitative immunoprecipitation combined with knock-down and crosslinking) to Chlamydomonas reveals the presence of VIPP1 in a common complex with chloroplast HSP90C. Proteomics, 11, 3079-3089.

33. Willmund, F., Dorn, V. K., Schulz-Raffelt, M., and Schroda, M. (2008) The chloroplast DnaJ homolog CDJ1 of Chlamydomonas reinhardtii is part of a multi-chaperone complex containing HSP70B, CGE1, and HSP90C. Plant Physiol.,148, 2070-2082.

32. Michelet, L., Zaffagnini, M., Vanacker, H., Le Marechal, P., Schroda, M., Lemaire, S. D., and Decottignies, P. (2008) In vivo targets of glutathionylation in Chlamydomonas reinhardtii. J. Biol. Chem.,283, 21571-21578.

31. Willmund, F., Hinnenberger, M., Nick, S., Schulz-Raffelt, M., Mühlhaus, T., and Schroda, M. (2008) Assistance for a chaperone: HEP2 activates plastidic HSP70B for cochaperone binding in Chlamydomonas.J. Biol. Chem., 283, 16363-16373.

30. Lodha, M., Schulz-Raffelt, M. and Schroda, M. (2008) A new assay for promoter analysis in Chlamydomonas reveals a role for heat shock elements and TATA-box in HSP70A promoter mediated activation of transgene expression. Eukaryot. Cell, 7, 172-176.

29. Merchant, S.S., Prochnik, S.E., Vallon, O., Harris, E.H., Karpowicz, S.J., Witman, G.B., Terry, A., Salamov, A., Fritz-Laylin, L.K., Marechal-Drouard, L., Marshall, W.F., Qu, L.H., Nelson, D.R., Sanderfoot, A.A., Spalding, M.H., Kapitonov, V.V., Ren, Q., Ferris, P., Lindquist, E., Shapiro, H., Lucas, S.M., Grimwood, J., Schmutz, J., Cardol, P., Cerutti, H., Chanfreau, G., Chen, C.L., Cognat, V., Croft, M.T., Dent, R., Dutcher, S., Fernandez, E., Fukuzawa, H., Gonzalez-Ballester, D., Gonzalez-Halphen, D., Hallmann, A., Hanikenne, M., Hippler, M., Inwood, W., Jabbari, K., Kalanon, M., Kuras, R., Lefebvre, P.A., Lemaire, S.D., Lobanov, A.V., Lohr, M., Manuell, A., Meier, I., Mets, L., Mittag, M., Mittelmeier, T., Moroney, J.V., Moseley, J., Napoli, C., Nedelcu, A.M., Niyogi, K., Novoselov, S.V., Paulsen, I.T., Pazour, G., Purton, S., Ral, J.P., Riano-Pachon, D.M., Riekhof, W., Rymarquis, L., Schroda, M., Stern, D., Umen, J., Willows, R., Wilson, N., Zimmer, S.L., Allmer, J., Balk, J., Bisova, K., Chen, C.J., Elias, M., Gendler, K., Hauser, C., Lamb, M.R., Ledford, H., Long, J.C., Minagawa, J., Page, M.D., Pan, J., Pootakham, W., Roje, S., Rose, A., Stahlberg, E., Terauchi, A.M., Yang, P., Ball, S., Bowler, C., Dieckmann, C.L., Gladyshev, V.N., Green, P., Jorgensen, R., Mayfield, S., Mueller-Roeber, B., Rajamani, S., Sayre, R.T., Brokstein, P., Dubchak, I., Goodstein, D., Hornick, L., Huang, Y.W., Jhaveri, J., Luo, Y., Martinez, D., Ngau, W.C., Otillar, B., Poliakov, A., Porter, A., Szajkowski, L., Werner, G., Zhou, K., Grigoriev, I.V., Rokhsar, D.S. and Grossman, A.R. (2007) The Chlamydomonas genome reveals the evolution of key animal and plant functions. Science, 318, 245-250.

28. Schulz-Raffelt, M., Lodha, M., and Schroda, M. (2007) Heat shock factor 1 is a key regulator of the stress response in Chlamydomonas. Plant J., 52, 286-295.

27. Liu, C., Willmund, F., Golecki, J. R., Cacace, S., Heß, B., Markert, C., and Schroda, M. (2007) The chloroplast HSP70B-CDJ2-CGE1 chaperones catalyze assembly and disassembly of VIPP1 oligomers in Chlamydomonas.Plant J., 50, 265-277.

26. Shao, N., Krieger-Liszkay, A., Schroda, M., and Beck, C. F. (2007) A reporter system for the individual detection of hydrogen peroxide and singlet oxygen: Its use for the assay of reactive oxygen species produced in vivo. Plant J., 50, 475-487.

25. Willmund, F., Mühlhaus, T., Wojciechowska, M., and Schroda, M. (2007) The NH2-terminal domain of the chloroplast GrpE homolog CGE1 is required for dimerization and cochaperone function in vivo.J. Biol. Chem.,282, 11317-11328.

24. Von Gromoff, E., Schroda, M., Oster, U., and Beck, C. F. (2006) Identification of a plastid response element that acts as an enhancer within the Chlamydomonas HSP70A promoter. Nucleic Acids Res., 34, 4767-4779.

23. Lodha, M. and Schroda, M. (2005) Analysis of chromatin structure in the control regions of the Chlamydomonas HSP70A and RBCS2 genes. Plant Mol. Biol. 59, 501-513.

22. Willmund, F. and Schroda, M. (2005) HSP90C is a bona-fide Hsp90 that interacts with plastidic HSP70B in Chlamydomonas reinhardtii.Plant Physiol. 138, 2310–2322.

21. Liu, C., Willmund, F., Whitelegge, J.P., Hawat, S., Knapp, B., Lodha, M., and Schroda, M. (2005). J-domain protein CDJ2 and HSP70B are a plastidic chaperone pair that interacts with vesicle inducing protein in plastids 1 (VIPP1). Mol. Biol. Cell. 16, 1165-1177.

20. Schroda, M., Beck, C. F. and Vallon, O (2002) Sequence elements within an HSP70 promoter counteract transcriptional transgene silencing in Chlamydomonas. Plant J. 31, 445-455.

19. Kaijalainen, S., Schroda, M. and Lindström, K. (2002) Cloning of nodule-specific cDNAs of Galega orientalis. Physiol. Plant.114, 588-593.

18. Schroda, M., Vallon, O., Whitelegge, J. P., Beck, C. F. and Wollman, F.-A. (2001) The chloroplastic GrpE homolog of Chlamydomonas: two isoforms generated by differential splicing. Plant Cell 13, 2823-2839.

17. Schroda, M., Blöcker, D. and Beck, C. F. (2000) The HSP70A promoter as a tool for the improved expression of transgenes in Chlamydomonas. Plant J. 21, 121-131.

16. Schroda, M., Vallon, O., Wollman, F.-A. and Beck, C. F. (1999) A chloroplast-targeted heat shock protein 70 (HSP70) contributes to the photoprotection and repair of photosystem II during and after photoinhibition. Plant Cell 11, 1165-1178.

15. Drzymalla, C., Schroda, M. and Beck, C. F. (1996) Light-inducible gene HSP70B encodes a chloroplast-localized heat shock protein in Chlamydomonas reinhardtii. Plant Mol. Biol. 31, 1185-1194.


B. Review articles

14. Theis, J. and Schroda, M. (2016) Revisiting the Photosystem II Repair Cycle. Plant Signal. Behav., in press.

13. Schroda, M., Hemme, D. and Muhlhaus, T. (2015) The Chlamydomonas heat stress response.Plant J., 82, 466-480.

12. Trösch, R., Mühlhaus, T., Schroda, M., and Willmund, F. (2015) ATP-dependent molecular chaperones in plastids - More complex than expected. Biochim. Biophys. Acta., 1847, 872-888.

11. Rütgers, M., Schroda, M. (2013) A role of VIPP1 as a dynamic structure within thylakoid centers as sites of photosystem biogenesis? Plant Signal. Behav., 8, e27037.

10. Nordhues, A., Miller, S. M., Mühlhaus, T., and Schroda, M. (2010) New insights into the roles of molecular chaperones in Chlamydomonas and Volvox. Int. Rev. Cytol. Mol. Biol., 285, 75-113.

9. Schroda, M and Mühlhaus, T. (2009) A foldosome in the chloroplast? Plant Signal. Behav., 4, 301-303.

8. Schroda, M. (2006) RNA silencing in Chlamydomonas – mechanisms and tools. Curr. Genet., 49, 69-84.

7. Schroda, M. (2004). The Chlamydomonas genome reveals its secrets: chaperone genes and the potential roles of their gene products in the chloroplast. Photosynth. Res. 82, 221-240.

6. Schroda, M., Kropat, J., Oster, U., Rüdiger, W., Vallon, O., Wollman, F.-A. and Beck, C. F. (2001) A role for molecular chaperones in assembly and repair of photosystem II? Biochem. Soc. Trans. 29, 413-418.

C. Book chapters, Internet and other publications

5. Hemme, D., Surulescu, C., Becker, H.M., Deitmer, J.W., Mühlhaus, T., Garth, C. and Schroda, M. (2015) BioComp - Analyse komplexer Datensätze in Lebenswissenschaften und Biotechnologie., 9, 68-71.

4. Trösch, R., Schroda, M., and Willmund, F. (2014) Molecular Chaperone Functions in Plastids. In:Advances in Plant Biology,325-357.

3. Hemme, D., Weiß, J., Mühlhaus, T., Sommer, F., and Schroda, M. (2010)Ein neues Verfahren zur Analyse von Änderungen der zellulären Proteinzusammensetzung in Pflanzen., 2, 40-42.

2. Schroda, M. and Vallon, O. (2008) Chaperones and Proteases. In: The Chlamydomonas Sourcebook, Second Edition: Elsevier / Academic Press, p. 671-729.

1. Schroda, M., Peak, S. and Gross, L. MENSTR (Version1.2 – 1/94). Computer program for the determination of menstrual cycles. Copyright 1994 – University of Tennessee, Knoxville (