Lecture Material 

Please find hereafter pdfs of the previous lecture courses:

26.10.2017 Basic laboratory practices and equipment (Johannes Herrmann)

02.11.2017 Modern cloning techniques (Felix Willmund)

09.11.2017 Modern microbiology techniques (Susanne Zehner)

16.11.2017 Protein enrichment and purification approaches (Ilka Haferkamp)

23.11.2017 Protein-protein interactions (Michael Schroda)

30.11.2017 Analysis of protein function and enzyme kinetics (Torsten Möhlmann)

14.12.2017 Yeast genetics (Bruce Morgan)

21.12.2017 An introduction to fluorescence microscopy (David Scheuring)

11.01.2018 Neuronal imaging and optogenetics (Jan Hirtz)

18.01.2018 Super-resolution Microscopy (Jan Pielage)

25.01.2018 Modern methods in structural biology (Markus Räschle)

01.02.2018 Uses and applications of detergents in biology (Sandro Keller)

for Master Students

Part Jun.-Prof. Morgan: Monday, April 23rd 2018 until Friday April 27th, 2018 in 13-443
Part Dr. Markus Räschle: Monday, April 30th, 2018 until Friday May 4th, 2018

Written Exam: May 18th, 2018 from 9.00 - 10.30 am in Mensa 1 - you can register at the Prüfungsamt in person as of May 2nd, 2018 for exam no. 70012

Retry Exam: June 22nd, 2018 from 9.00 - 10.30 am in Mensa 1 - you can register at the Prüfungsamt in person as of May 2nd, 2018 until June 15th, 2018 for exam no. 70012/2

Topics 2018

 1 Mitochondrial machineries for protein import and assembly
 2 MitoCPR- A surveillance pathway that protects mitochondria in response to protein import stress
 3 Role of the mitochondrial contact site and cristae organizing system in membrane architecture dynamics
 4 Central role of Mic10 in the mitochondrial contact site and cristae organizing system
 5 The mitochondrial respiratory chain
 6 Structure of a complete ATP synthase dimer reveals the molecular basis of inner mitochondrial
  membrane morphology
 7 Complementation of mitochondrial electron transport chain by manipulation of the NAD-NADH ratio
 8 Functional metabolomics describes the yeast biosynthetic regulome
 9 The conundrum of H2O2 signaling and the emerging role of peroxiredoxins as redox relay hubs
10 A role for 2-cys peroxiredoxins in facilitating cytosolic protein thiol oxidation
11 Glutathione revisited- a vital function in iron metabolism and ancillary role in thiol-redox control
12 Multiple glutathione disulfide removal pathways mediate cytosolic redox homeostasis
13 Endoplasmic reticulum transport of glutathione by Sec61 is regulated by Ero1 and Bip1
14 Cellular timekeeping- it's redox o' clock
15 Peroxiredoxins are conserved markers of circadian rhythms
16 Real-time monitoring of basal H2O2 levels with peroxiredoxin-based probes

Practical Courses

The practical course “Molecular Biology” for first year students (GM4) takes place after the winter term. It is a two week course of which the first week is arranged by the divisions of Cellular Biochemistry and Cellular Biology. Please sign up for this course in the KIS system. If you have questions, please contact me by email (morgan@bio.uni-kl.de).

Further practical courses (AP, VP) are performed together with the division of Cellular Biology (Prof. Johannes Herrmann). Participation in at least one of the three-week practical courses (Winter Term and/or Summer Term) also is a prerequisite for a research practical, bachelor or master theses in our laboratory.

Next practical courses:

• GM4 - Teil Zellbiologie: 03.04.2017 - 07.04.2017 in den Räumen 13-322 und 13-347