Fachgebiet Genetik


  • Starcevic A., Wolf K., Diminic J., Zucko J., Trninic Ruzic I., Long P.F., Hranueli D., Cullum J. (2011) Recombinatorial biosynthesis of polyketides. J Ind Microbiol Biotechnol, online ahead of print, doi: 10.1007/s10295-011-1049-x
  • Zucko J., Dunlap W.C., Shick J.M., Cullum J., Cercelet F., Amin B., Hammen L., Lau T., Williams J., Hranueli D., Long P.F.. (2010) Global genome analysis of the shikimic acid pathway reveals greater gene loss in host-associated than in free-living bacteria. BMC Genomics. 11:628
  • Zucko J., Cullum J.., Hranueli D., Long P.F. (2011) Evolutionary dynamics of modular polyketide synthases, with implications for protein design and engineering. J Antibiot (Tokyo). 64:89-92
  • Starcevic A., Dunlap W.C., Cullum J., Shick J.M., Hranueli D., Long P.F.. (2010) Gene expression in the scleractinian Acropora microphthalma exposed to high solar irradiance reveals elements of photoprotection and coral bleaching. PLoS One. 5:e13975
  • Starcevic A., Diminic J., Zucko J., Elbekali M., Schlosser T., Lisfi M., Vukelic A., Long P.F., Hranueli D., Cullum J. (2011) A novel docking domain interface model predicting recombination between homoeologous modular biosynthetic gene clusters. J Ind Microbiol Biotechnol. 13: 1295-1304
  • Goldstein P., Zucko J., Vujaklija D., Krisko A., Hranueli D., Long P.F., Etchebest C., Basrak B., Cullum J. (2009) Clustering of protein domains for functional and evolutionary studies. BMC Bioinformatics 10:335
  • Bruce-Micah R., Hüttenberger D., Freitag L., Cullum J., Foth H.-J. (2009) Pharmacokinetics of ALA and h-ALA induced porphyrins in the models Mycobacterium phlei and Mycobacterium smegmatis. J Photochem Photobiol B 97:1-7
  • Soror SH., Rao Ren, Cullum J. (2009) Mining the genome sequence for novel enzyme activity: characterisation of an unusual member of the hormone-sensitive lipase family of esterases from the genome of Streptomyces coelicolor A3(2). Protein Eng Des Sel 22:333-339
  • Castaldo G., Zucko J., Heidelberger S., Vujaklija D., Hranueli D., Cullum J., Wattana-Amorn P, Crump MP, Crosby J, Long PF (2008) Proposed Arrangement of Proteins Forming a Bacterial Type II Polyketide Synthase. Chem Biol. 15:1156-1165
  • Starcevic A., Zucko J., Simunkovic J., Long P. F., Cullum J., Hranueli D. (2008) ClustScan: An integrated program package for the semi-automatic annotation of modular biosynthetic gene clusters and in silico prediction of novel chemical structures. Nucleic Acids Res. 36: 6882-6892
  • Starcevic A., Akthar S., Dunlap W.C., Shick M., Hranueli D., Cullum J., Long P.F. (2008) Enzymes of the shikimic acid pathway encoded in the genome of a basal metazoan, Nematostella vectensis, have microbial origins. PNAS 105: 2533-2537