Division of Pflanzenphysiologie



Bellin L, Garza Amaya AD, Scherer V, Pruss T, John A, Richter A, Moehlmann T* (2023) Nucleotide imbalance, provoked by downregulation of Aspartate transcarbamoylase impairs cold acclimation in Arabidopsis. Molecules, accepted



Okooboh GO, HaferkampI, Valifard M, Pommerrenig B, Kelly A, Feussner I, Neuhaus HE (2022) Overexpression of the vacuolar sugar importer BvTST1 from sugar beet in Camelina improves seed properties and leads to altered root characteristics. Physiol. Plant., 174 e13653, doi: 10.1111/ppl.13653

Krämer M, Dörfer E, Hickl D, Bellin L, Scherer VD, Möhlmann T (2022) CTP-Synthase 4 (CTPS4) from Arabidopsis thaliana attenuates drought stress effects. Front. Plant Science-Plant Abiotic Stress, https://www.frontiersin.org/articles/10.3389/fpls.2022.842156/

Wen S, Neuhaus HE, Cheng J, Bie Z (2022) Contributions of sugar transporters to crop yield and fruit quality. J. Exp. Bot. 73, 2275–2289, DOI: doi: 10.1093/jxb/erac043

Ko HY, Tseng H-W, Ho L-H, Wang L, Chang T-F, Lin A, Ruan Y-L, Neuhaus HE, Guo YW (2022) Hexose translocation mediated by SlSWEET5b is required for pollen maturation in Solanum lycopersicum. Plant Physiol., 189, 344–359 doi: 10.1093/plphys/kiac057

Gutschker S, Coral JM, Schmiedl A, Ludewig F, Koch W, Fiedler-Wiechers K, Czarnecki O, Harms K, Keller I, Martins Rodrigues C, Pommerrenig B, Neuhaus HE, Zierer W, Sonnewald U, Müdsam C (2022) Multi-omics data integration reveals link between epigenetic modifications and gene expression in sugar beet (Beta vulgaris subsp. vulgaris) in response to cold. BMC Genomics 23, 144  doi: 10.1186/s12864-022-08312-2

Schwenkert S, Fernie AR, Geigenberger P, Leister D, Möhlmann T, Naranjo B, Neuhaus HE (2022) Chloroplasts are key players to cope with light and temperature stress. Trends in Plant Sci. 27, 577-587 doi: 10.1016/j.tplants.2021.12.004

Altensell JS, Wartenberg R, Haferkamp I, Hassler S, Scherer V, Steensma P, Fitzpatrick TB, Sharma A, Ibañez OS, Pribil M, Lehmann M, Leister D, Kleine T, Neuhaus HE (2022) Inactivation of a pyridoxal-phosphate phosphatase suppresses the dwarf growth of Arabidopsis er-ant1 mutants. Plant Physiol. 189, 49–65  doi: 10.1093/plphys/kiac048/6525245 

Aubry E, Hoffmann B, Vilaine F, Gilard F, Klemens PAW, Guérard F, Gakière B, Neuhaus HE, Bellini C, Dinant S, Le Hir R (2022) A vacuolar hexose transport is required for xylem development in the inflorescence stem. Plant Physiol. 188, 1229-1247, doi: 10.1093/plphys/kiab551


Bellin L, Scherer V, Dörfer E, Lau A, Vicente A, Meurer J, Hickl D, Möhlmann T (2021) Cytosolic CTP production limits the establishment of photosynthesis in Arabidopsis. Front. Plant Science-Plant Physiology, 12, 789189  doi: 10.3389/fpls.2021.789189. eCollection 2021

Valifard M, LeHir R, Müller J, Scheuring D, Neuhaus HE, Pommerrenig B (2021) The vacuolar fructose transporter SWEET17 is critical for Arabidopsis root development and drought tolerance. Plant Physiol. 187, 2716-2730 doi: 10.1093/plphys/kiab436

Hickl D*, Drews F*, Girke C, Zimmer D, Mühlhaus T, Hauth J, Nordström K, Trentmann O, Neuhaus HE, Scheuring D, Fehlmann T, Keller A, Simon M, Möhlmann T (2021) Differential degradation of RNA species by autophagy related pathways in Arabidopsis. J. Exp. Bot., 72, 6867-6881 doi: 10.1093/jxb/erab321
*authors contributed equally

Ko H-Y, Ho L-H, Neuhaus HE, Guo W-J (2021) SlSWEET15 is involved in sucrose unloading from phloem and seed coat for fruit and seed development in tomato. Plant Physiol. 187, 2230-2245 doi: 10.1093/plphys/kiab290

Keller I, Müdsam C, Martins Rodrigues C, Kischka D, Zierer W, Sonnewald U, Harms K, Czarnecki O, Fiedler-Wiechers K, Koch W, Neuhaus HE, Ludewig F, Pommerrenig B (2021) Cold-triggered induction of ROS-and raffinose metabolism in freezing-sensitive taproot tissue of sugar beet. Front. Plant Sci. 12, 1886  doi: 10.3389/fpls.2021.715767  

Klionsky DJ et al. (2021) Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy 8, 1-382 doi: 10.1080/15548627.2020.1797280

Rüscher D, Corral García JM, Carluccio AV, Klemens PAW, Gisel A, Stavolone L, Neuhaus HE, Ludewig F, Sonnewald U, Zierer W (2021) Auxin signaling and vascular cambium formation enables storage metabolism in cassava tuberous roots. J. Exp. Bot. 72,  3688–3703  doi: 10.1093/jxb/erab106

Hickl D, Scheuring D, Möhlmann T (2021) CTP-Synthase 2 from Arabidopsis thaliana is required for complete embryo development. Front. Plant Sci. 12, 652434 doi 10.3389/fpls.2021.652434

Bellin L, Del Caño-Ochoa F, Velázquez-Campoy A, Möhlmann T*, Ramón-Maiques S* (2021) Mechanisms of feedback inhibition and sequential firing of active sites in plant aspartate transcarbamoylase. Nat. Commun. 12, 947  doi: 10.1038/s41467-021-21165-9 (*shared corresponding authorship)

Cvetkovic J, Haferkamp I, Rode R, Keller I, Pommerrenig B, Trentmann O, Altensell J, Fischer-Stettler M, Eicke S, Zeeman SC, Neuhaus HE (2021) Ectopic maltase alleviates dwarf phenotype and improves plant frost tolerance of maltose transporter mutants. Plant Physiol. 186, 315-329 doi 10.1093/plphys/kiab082

Korobova A, Kuluev B, Möhlmann T, Veselov D, Kudoyarova G (2021) Limitation of cytokinin export to the shoots by nucleoside transporter ENT3 and its linkage with root elongation in Arabidopsis. Cells 2021, 10, 350 doi: 10.3390/cells10020350

Keller I, Martins Rodrigues C, Neuhaus HE, Pommerrenig B (2021) Improved resource allocation and stabilization of yield under abiotic stress. J. Plant Physiol. 257, 153336 doi: 10.1016/j.jplph.2020.153336

Kleine T, Naegele T, Neuhaus HE, Schmitz-Linneweber C, Fernie A, Geigenberger P, Grimm B, Kaufmann K, Klipp E, Meurer J, Möhlmann T, Mühlhaus T, Naranjo B, Nickelsen J, Richter AS, Ruwe H, Schroda M, Schwenkert S, Trentmann O, Willmund F, Zoschke R, Leister D (2020) Acclimation in plants – the Green Hub consortium. Plant J. 106, 23-40 doi: 10.1111/tpj.15144 

Ho, L-H*, Lee Y-I*, Hsieh S-Y, Lin I-S, Wu Y-C, Ko H-Y, Klemens PAW, Neuhaus HE, Chen Y-M, Huang T-P, Yeh C-H, Guo W-J (2021) GeSUT4 mediates sucrose import at the symbiotic interface for carbon allocation of heterotrophic Gastrodia elata (Orchidaceae). Plant Cell Environ. 44, 20-33  doi: 10.1111/pce.13833


Ho, L-H, Rode R, Siegel M, Reinhardt F, Neuhaus HE, Yvin J-C, Pluchon S, Hoseini SA, Pommerrenig B (2020) Potassium application boosts photosynthesis and sorbitol biosynthesis and accelerates cold acclimation of common plantain (Plantago major L.). Plants 2020 9, 1259 doi: 10.3390/plants9101259

Martins Rodrigues C*, Müdsam C*, Keller I, Zierer W, Czarnecki O, Corral JM, Reinhardt F, Nieberl P, Fiedler-Wiechers K, Sommer FK, Schroda M, Mühlhaus T, Harms K, Flügge UI, Sonnewald U, Koch W, Ludewig F, Neuhaus HE, Pommerrenig B (2020) Vernalization alters sink and source identities and reverses phloem translocation from taproots to shoots in sugar beet (Beta vulgaris). Plant Cell 32, 3206–3223 doi: 10.1105/tpc.20.00072 
(*These authors contributed equally to this work)

Vu DP, Martins Rodrigues C, Jung B, Meissner G, Klemens PAW, Holtgräwe D, Fürtauer L, Nägele T, Nieberl P, Pommerrenig P, Neuhaus HE (2020) Vacuolar sucrose homeostasis is critical for plant development, seed properties, and night-time survival in Arabidopsis. J. Exp. Bot. 71, 4930-4943 doi: 10.1093/jxb/eraa205 
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Pommerrenig B, Müdsam C, Kischka D, Neuhaus HE (2020) Treat and trick: common regulation and manipulation of sugar transporters during sink establishment by the plant and the pathogen. J. Exp. Bot. 71, 3930-3940 doi: 10.1093/jxb/eraa168

Duscha K, Martins Rodrigues C, Müller M, Wartenberg R, Fliegel L, Deitmer JW, Jung M, Zimmermann R, Neuhaus HE (2020) 14-3-3 proteins and other candidates form protein-protein interactions with the cytosolic C-terminal end of SOS1 affecting its transport activity. Int. J. Mol. Sci. 21, 3334 doi: 10.3390/ijms21093334

Feitosa-Araujo E, Chaves I, Florian A, da Fonseca-Pereira P, Condori Apfata JA, Heyneke E, Medeiros DB, Pires MV, Mettler-Altmann T, Neuhaus HE, Palmieri F, Araújo WL, Obata T, Weber APM, Linka N, Fernie A, Nunes-Nesi A (2020) Down-regulation of a mitochondrial NAD+ transporter (NDT2) alters seed production and germination in Arabidopsis. Plant Cell Phys. 61, 897-908 doi: 10.1093/pcp/pcaa017

Fernie AR, Bachem CWB, Helariutta Y, Neuhaus HE, Prat S, Ruan Y-L, Stitt M, Sweetlove LJ, Tegeder M, Wahl V, Sonnewald S, Sonnewald U (2020) Synchronisation of developmental, molecular and metabolic aspects of source-sink interactions.  Nat. Plants 6, 55-66 doi: 10.1038/s41477-020-0590-x

Obata T, Klemens P, Rosado de Sousa L, Schlereth A, Gisel A, Stavolone L, Zeier W, Morales N, Mueller L, Zeeman S, Ludewig F, Stitt M, Sonnewald U, Neuhaus HE, Fernie A (2020) Metabolic profiles of six African cultivars of cassava (Manihot esculenta Crantz)  highlight bottlenecks of root yield. Plant J. 102, 1202-1219doi: 10.1111/tpj.14693

Grunewald S, Marillonnet S, Hause G, Haferkamp I, Neuhaus HE, Veß A, Hollemann T, Vogt T (2020) The tapetal major facilitator NPF2.8 is required for accumulation of flavonol glycosides on the pollen surface in Arabidopsis thaliana. Plant Cell 32, 1727-1748 doi: 10.1105/tpc.19.00801

Trentmann O, Mühlhaus T, Zimmer D, Sommer FK, Schroda M, Haferkamp I, Keller I, Pommerrenig B, Neuhaus HE (2020) Identification of chloroplast envelope proteins with critical importance for cold acclimation. Plant Physiol. 182, 1239-1255doi: 10.1104/pp.19.00947


Ho L-S, Klemens PAW, Neuhaus HE, Ko H-Y, Hsieh S-Y, Guo WJG (2019) SlSWEET1a is involved in glucose import to young leaves in tomato plants J. Exp. Bot. 70, 3241-3254 doi: 10.1093/jxb/erz154

Rosado-Souza L, David LC, Drapal M, Fraser PD, Hofmann J, Klemens PAW, Ludewig F, Neuhaus HE, Obata T, Perez-Fons L, Schlereth A, Sonnewald U, Stitt M, Zeeman SC, Zierer W, Fernie AR (2019) Cassava metabolomics and starch quality. Curr. Prot. Plant Biol. Dec;4(4):e20102. doi: 10.1002/cppb.20102

de Souza Chaves I, Feitosa-Araújo E, Florian A, Medeiros DB, da Fonseca-Pereira P, Charton L, Heyneke E, Apfata JAC, Pires MV, Mettler-Altmann T, Araújo WL, Neuhaus HE, Palmieri F, Obata T, Weber APM, Linka N, Fernie AR, Nunes-Nesi A (2019) The mitochondrial NAD+ transporter (NDT1) plays important roles in cellular NAD+ homeostasis in Arabidopsis thaliana. Plant J. 100, 487-504 doi: 10.1111/tpj.14452

Ohler L, Niopek-Witz S, Mainguet SM, Möhlmann T (2019) Physiological function of pyrimidine salvage and interaction with chloroplast biogenesis. Plant Physiol. 180, 1816-1828 doi: 10.1104/pp.19.00329

Rohr M, Ries F, Herkt C, Gotsmann VL, Westrich LD, Gries K, Trösch R, Christmann J, Chaux-Jukic F, Jung M, Zimmer D, Mühlhaus T, Sommer F, Schroda M, Keller S, Möhlmann T, Willmund F (2019) The role of plastidic trigger factor serving protein biogenesis in green algae and land plants. Plant Physiol. 179, 1093-1110 doi: 10.1104/pp.18.01252

Ashykhmina N, Lorenz M, Frerigmann H, Koprivova A, Hofsetz E, Stührwohldt N, Flügge U-I, Haferkamp I, Kopriva S, Gigolashvili T (2019) PAPST2 plays critical roles in removing the stress signaling molecule 3' Phosphoadenosine 5'-Phosphate from the cytosol and its subsequent degradation in plastids and mitochondria. Plant Cell 31, 231-249 doi: 10.1105/tpc.18.00512

Schmid LM, Ohler L, Möhlmann T, Brachmann A, Muino JM, Leister D, Meurer J, Manavski N (2019) PUMPKIN, the sole plastid UMP kinase, associates with group II introns and alters their metabolism. Plant Physiol. 179, 248-264 doi: 10.1104/pp.18.00687

Patzke K*, Prananingrum P*, Klemens PAW, Trentmann O, Martins Rodrigues C, Keller I, Fernie AR, Geigenberger P, Bölter B, Lehmann M, Schmitz-Esser C, Pommerrenig B, Haferkamp I, Neuhaus HE (2019) The plastidic sugar transporter pSuT influences flowering and affects cold responses. Plant Physiol. 179, 569-587 doi: 10.1104/pp.18.01036
*These authors contributed equally to the article


Pommerrenig B, Ludewig F, Cvetkovic J, Trentmann O, Klemens PAW, Neuhaus HE (2018) In concert: Orchestrated changes in carbohydrate homeostasis are critical for plant abiotic stress tolerance. Plant Cell Phys. 59, 1290-1299 doi: 10.1093/pcp/pcy037

Klein M-C, Zimmermann K, Schorr S, Landini M, Klemens PAW, Altensell J, Jung M, Krause E, Nguyen D, Helms V, Rettig J, Fecher-Trost C, Cavalié A, Hoth M, Bogeski I, Neuhaus HE, Zimmermann R, Lang S, Haferkamp I (2018) AXER is an ATP/ADP exchanger in the membrane of the endoplasmic reticulum. Nature Comm. volume 9, Article number: 3489 doi: 10.1038/s41467-018-06003-9

Shammai A, Petreikov M, Yeselson Y, Faigenboim A, Moy-Komemi M, Cohen S, Cohen D, Besaulov E, Efrati A, Houminer N, Bar M, Ast T, Schuldiner M, Klemens PAW, Neuhaus HE, Baxter C, Rickett D, Bonnett J, White R, Giovannoni J, Levin I, Schaffer AA (2018) Natural genetic variation for expression of a SWEET transporter among wild species of tomato determines the hexose composition of ripening tomato fruit. Plant J. 96, 343-357 doi 10.1111/tpj.14035 

Daumann M, Hickl D, Zimmer D, De Tar RA, Kunz H-H, Möhlmann T (2018) Characterization of filament-forming CTP synthases from Arabidopsis thaliana. Plant J. 96, 316-328 doi: 10.1111/tpj.14035

Huang W, Haferkamp I, Lepetit B, Molchanova M, Huo S, Jeblick W, Río Bártulos C, Kroth PG (2018) Reduced vacuolar ß-1,3-glucan synthesis affects carbohydrate metabolism as well as plastid homeostasis and structure in Phaeodactylum tricornutum. PNAS 115, 4791-4796 doi: 10.1073/pnas.1719274115

Graus D, Konrad KR, Bemm F, Patir Nebioglu MG, Lorey C, Duscha K, Güthoff T, Herrmann J, Ferjani A, Cuin TA, Roelfsema MRG, Schumacher K, Neuhaus HE, Marten I, Hedrich R (2018) High V-PPase activity is beneficial under high salt loads, but detrimental without salinity. New Phytol. 219, 1421-1432 doi: 10.1111/nph.15280

Frei B, Eisenach C, Martinoia E, Hussein S, Chen X-Z, Arrivault S, Neuhaus HE (2018) Purification and functional characterization of the vacuolar malate transporter tDT from Arabidopsis. J. Biol. Chem. 293, 4180-4190 doi: 10.1074/jbc.RA117.000851

Haferkamp (2018) Crossing the border - Solute entry into the chlamydial inclusion. Int. J. Med. Microbiol. 308, 41-48 doi: 10.1016/j.ijmm.2017.08.006


Ferreira SJ, Senning M, Fischer-Stettler M, Streb S, Ast M, Neuhaus HE, Zeeman SC, Sonnewald S, Sonnewald U (2017) Simultaneous silencing of isoamylases ISA1, ISA2 and ISA3 by multi-target RNAi in potato tubers leads to decreased starch content and an early sprouting phenotype. PLoS ONE 12(7): e0181444.
doi: 10.1371/journal.pone.0181444 

Nieberl P, Ehrl C, Pommerrenig B, Graus D, Marten I, Jung B, Ludewig F, Koch W, Harms K, Flügge U-I, Neuhaus HE, Hedrich R, Sauer N (2017) Functional characterisation and cell specificity of BvSUT1, the transporter that loads sucrose into the phloem of sugar beet (Beta vulgaris L.) source leaves. Plant Biol. 19, 315-326 doi: 10.1111/plb.12546

Fahy D, Sanad MNME, Duscha K, Lyons M, Liu F, Bozhkov P, Kunz H-H, Hu J, Neuhaus NE, Steel PG, Smertenko A (2017) Impact of salt stress, cell death, and autophagy on peroxisomes: quantitative and morphological analyses using small fluorescent probe N-BODIPY. Scientific Rep. | 7:39069 | doi: 10.1038/srep39069

Chu L, Gruber A, Ast M, Schmitz-Esser S, Altensell J, Neuhaus HE, Kroth PG, Haferkamp I (2017) Shuttling of (deoxy-) purine nucleotides between compartments of the diatom Phaeodactylum tricornutum. New Phytol. 113, 193-205 doi: 10.1111/nph.14126


Daumann M, Golfier P, Knüppel N, Hahn M, Möhlmann T (2016) Botrytis cinerea can import and utilize nucleosides in salvage and catabolism and BcENT functions as high affinity nucleoside transporter. Fungal Biology 120, 904-916 doi: 10.1016/j.funbio.2016.05.012

Hassler S, Jung B, Lemke L, Novák O, Strnad M, Martinoia E, Neuhaus HE (2016) Function of the Golgi-located phosphate transporter PHT4;6 is critical for senescence-associated processes in Arabidopsis. J. Exp. Bot. 67, 4671-4684 doi: 10.1093/jxb/erw249

Pertl-Obermeyer H, Duscha K, Trentmann O, Neuhaus HE, Schulze WX (2016) Quantitation of vacuolar sugar transporter abundance changes using QconCAT synthtetic peptides. Front. Plant Sci. 7:411  doi: 10.3389/fpls.2016.00411


Daumann M, Fischer M, Niopek-Witz S, Girke C, Möhlmann T (2015) Apoplastic nucleoside accumulation in Arabidopsis leads to reduced photosynthetic performance and increased susceptibility against Botrytis cinerea. Front. Plant Sci. 6:1158 doi: 10.3389/fpls.2015.01158

Lorenz A, Lorenz M, Vothknecht U, Niopek-Witz S, Neuhaus HE, Haferkamp I (2015) In vitro analyses of mitochondrial ATP/phosphate carriers from Arabidopsis thaliana revealed unexpected Ca2+-effects. BMC Plant Biol. 2015; 15: 238 doi: 10.1186/s12870-015-0616-0

LeHir R, Spinner L, Klemens PAW, Chakraborti D, De Marco F, Vilaine F, Wolff N, Lemoine R, Porcheron B, Géry C, Téoulé E, Chabout S, Mouille G, Neuhaus HE, Dinant S, Bellini C (2015) Disruption of the sugar transporters AtSWEET11 and AtSWEET12 affects vascular development and freezing tolerance in Arabidopsis. Mol. Plant 8, 1687–1690 doi: 10.1016/j.molp.2015.08.007

Girke C, Arutyunova E, Syed M, Traub M, Möhlmann T, Lemieux MJ (2015) High yield expression and purification of equilibrative nucleoside transporter 7 (ENT7) from Arabidopsis thaliana. Biochim. Biophys. Acta 1850, 1921-1929 doi: 10.1016/j.bbagen.2015.06.003

Hedrich R, Sauer N, Neuhaus HE (2015) Sugar transport across the plant vacuolar membrane: nature and regulation of carrier proteins. Curr. Opin. Plant Biol. 25, 63-70 doi: 10.1016/j.pbi.2015.04.008

Jung B, Ludewig F, Schulz A, Meißner G, Wöstefeld N, Flügge U-I, Pommerrenig B, Wirsching P, Sauer N, Koch W, Sommer F, Mühlhaus T, Schroda M, Cuin, TA, Graus D, Marten I, Hedrich R, Neuhaus HE (2015) Identification of the transporter responsible for sucrose accumulation in sugar beet taproots. Nature Plants 1, Article number: 14001 (2015), ​doi: 10.1038/nplants.2014.1
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Trentmann O, Neuhaus HE (2014) Regulation of transport processes across the tonoplast membrane. Plant Traffic and Transport. Review, Front. Plant Sci., 10 September 2014 | doi: 10.3389/fpls.2014.00460

Girke C, Daumann D, Niopek-Witz S, Möhlmann T (2014) Nucleobase and nucleoside transport and integration into plant metabolism. Review, Front. Plant Sci., 09 September 2014 doi: 10.3389/fpls.2014.00443

Niopek-Witz S, Deppe J, Lemieux MJ, Möhlmann T (2014) Biochemical characterization and structure-function relationship of two plant NCS2 proteins, the nucleobase transporters NAT3 and NAT12 from Arabidopsis thaliana. BBA – Biomembranes 1838, 3025-3035 doi: 10.1016/j.bbamem.2014.08.013

Ewald RA, Hoffmann C, Florian A, Neuhaus HE, Fernie AR, Bauwe H (2014) Lipoate-Protein Ligase and octanoyltransferase are essential for protein lipoylation in mitochondria of Arabidopsis. Plant Physiol. 165, 978-990 doi: 10.1104/pp.114.238311

Cohen S, Itkin M, Yeselson Y, Tsuri G, Portnoy V, Harel-Beja R, Lev S, Sa'ar U, Davidovitz-Rekanati R, Baranes N, Bar E, Wolf D, Petreikov M, Shen S, Ben-Dor S, Rogachev I, Aharoni A, Ast T, Schuldiner M, Belausov E, Eshed R, Ophir R, Sherman A, Frei B, Neuhaus HE, Xu Y, Fei Z, Giovannoni J, Lewinsohn E, Tadmor Y, Paris H, Katzir N, Burger Y, Schaffer A (2014) The PH gene determines fruit acidity and contributed to the evolution of sweet melons. Nature Comm. 5, Article number: 4026 doi: 10.1038/ncomms5026

Müller M, Kunz HH, Schroeder JI, Kemp G, Young HS, Neuhaus HE (2014) Decreased capacity of sodium export out of Arabidopsis chloroplasts impairs salt tolerance, photosynthesis and plant performance. Plant J. 78, 646–658 doi: 10.1111/tpj.12501

Witz S, Panwar P, Schober M, Deppe J, Pasha FA, Lemieux MJ, Möhlmann T (2014) Structure-function relationship of a plant NCS1 member - homology modeling and mutagenesis identified residues critical for substrate specificity of PLUTO a nucleobase transporter from Arabidopsis. PLOS ONE, doi: 10.1371/journal.pone.0091343

Colesie C, Allan Green GT, Haferkamp I, Büdel, B (2014) Habitat stress initiates changes in composition, CO2 gas exchange and C-allocation as life traits in biological soil crusts. ISME J. 8, 2104-2115  doi: 10.1038/ismej.2014.47

Klemens PAW, Patzke K, Trentmann O, Poschet G, Büttner M, Schulz A, Marten I, Hedrich R, Neuhaus HE (2014) Overexpression of a proton-coupled vacuolar glucose exporter impairs freezing tolerance and seed germination. New Phytol. 202, 188-197 doi: 10.1111/nph.12642

Ewald R, Hoffmann C, Neuhaus HE, Bauwe H (2014) Two redundant octanoyltransferases and one obligatory lipoyl synthase provide protein-lipoylation autonomy to plastids of Arabidopsis. Plant Biol. 16, 35-42 doi: 10.1111/plb.12028

Selinski J, Koenig N, Wellmeyer B, Hanke GT, Linke V, Neuhaus HE, Scheibe R (2014) The plastid-localized NAD-dependent malate dehydrogenase is crucial for energy homeostasis in developing Arabidopsis thaliana seeds. Molecular Plant. 7, 170–186 doi: 10.1104/pp.113.233866

Möhlmann T, Steinebrunner I, Neuhaus HE (2014) Nucleotides and nucleosides: transport, metabolism and signaling function of extracellular ATP. Progress in Botany In: Progress in Botany 75, Lüttge U, Beyschlag W, Cushman J (eds) Springer, pp. 119-144  


Klemens PAW, Patzke K, Deitmer J, Spinner L, Le Hir R, Bellini C, Bedu M, Chardon F, Krapp A, Neuhaus HE (2013) Overexpression of the vacuolar sugar carrier AtSWEET16 modifies germination, growth and stress tolerance in Arabidopsis thaliana. Plant Physiol. 163, 1338-1352 doi: 10.1104/pp.113.224972

Diez-de-Medina Roldán S, Silva H, Jeblick W, Nowik I, Modigell M, Neuhaus HE, Conrath U (2013) Profiling carbohydrate composition, biohydrogen capacity, and disease resistance in potato. Electr. J. Biotech. Vol. 16, No. 6 doi 10.2225/vol16-issue6-fulltext-4

Hoffmann C, Plocharski B, Haferkamp I, Leroch M, Ewald R, Bauwe H, Riemer J, Herrmann J, Neuhaus HE (2013) From Endoplasmic Reticulum to mitochondria: Absence of the Arabidopsis ATP antiporter ER-ANT1 perturbs photorespiration. Plant Cell 25, 2647-2660 doi: 10.1105/tpc.113.113605

Haferkamp I, Penz T, Geier M, Ast M, Mushak T, Horn M, Schmitz-Esser S (2013) The endosymbiont Amoebophilus asiaticus encodes an S-adenosylmethionine carrier compensating for its missing methylation cycle. J. Bacteriol. 195, 3183-3192 doi: 10.1128/JB.00195-13

Chardon F, Bedu M, Calenge F, Klemens PAW, Spinner L, Clement G, Chietera G, Léran S, Ferrand M, Lacombe B, Loudet O, Dinant S, Bellini C, Neuhaus HE, Daniel-Vedele F, Krapp A (2013) Leaf fructose content is controlled by the vacuolar transporter SWEET17 in Arabidopsis. Current Biology 23, 697-702 doi: 10.1016/j.cub.2013.03.021

Trentmann O, Haferkamp I (2013) Current progress in tonoplast proteomics reveals insights into the function of the large central vacuole. Front. Plant Sci., 01 March 2013 | doi: 10.3389/fpls.2013.00034


Gigolashvili T*, Geier M*, Ashykhmina N, Frerigmann F, Wulfert S, Krueger S, Mugford SG, Kopriva S, Haferkamp I, Flügge UI (2012) The Arabidopsis thylakoid ADP/ATP carrier TAAC has a primary role in supplying plastidic phosphoadenosine 5'-phosphosulfate (PAPS) to the cytosol. Plant Cell 24, 4187-4204 doi: 10.1105/tpc.112.101964
*both authors contributed equally to this paper

Hildenbeutel M, Theis M, Geier M, Haferkamp I, Neuhaus HE, Herrmann JM, Ott M (2012) The membrane insertase Oxa1 is required for efficient import of carrier proteins into mitochondria. J. Mol. Biol. 423, 590-599 doi: 10.1016/j.jmb.2012.07.018

Hassler S, Lemke L, Jung B, Möhlmann T, Krüger F, Schumacher Karin, Espen L, Martinoia E, Neuhaus HE (2012) Lack of the Golgi phosphate transporter PHT4;6 causes strong developmental defects, constitutively activated disease resistance mechanisms and altered intracellular phosphate compartmentation in Arabidopsis. Plant J. 72, 732-744 doi: 10.1111/j.1365-313X.2012.05106.x

Haferkamp I, Linka N (2012) Functional expression and characterisation of membrane transport proteins. Plant Biol. 14, 675-690 doi: 10.1111/j.1438-8677.2012.00591.x

Gebert M, Schrempp SG, Mehnert CS, Heißwolf AK, Oeljeklaus S, Ieva R, Bohnert M, von der Malsburg K, Wiese S, Kleinschroth T, Hunte C, Meyer HE, Haferkamp I, Guiard B, Warscheid B, Pfanner N, van der Laan M. (2012) Mgr2 promotes coupling of the mitochondrial presequence translocase to partner complexes. J Cell Biol. 197, 595-604 doi: 10.1083/jcb.201110047

Witz S*, Jung B*, Fürst S, Möhlmann T (2012) De novo pyrimidine nucleotide synthesis mainly locates outside of plastids, but a novel nucleobase importer provides substrates for the essential salvage pathway. Plant Cell 24, 1549-1559 doi: 10.1105/tpc.112.096743
*Both authors contributed equally to this paper

Haferkamp I, Schmitz-Esser S (2012) The plant mitochondrial carrier family: functional and evolutionary aspects. Frontiers in Plant Traffic and Transport Front. Plant Sci. 3:2. doi: 10.3389/fpls.2012.00002

Schulze W, Schneider T, Starck S, Martinoia E, Trentmann O (2012) Cold acclimation induces changes in Arabidopsis tonoplast protein abundance and activity and alters phosphorylation of tonoplast monosaccharide transporters. Plant J 69, 529-541 doi: 10.1111/j.1365-313X.2011.04812.x

Cornelius S, Traub M, Bernard C, Salzig C, Lang P, Möhlmann T (2012) Nucleoside transport across the plasma membrane mediated by equilibrative nucleoside transporter 3 influences metabolism of Arabidopsis seedlings. Plant Biol. 14, 696-705 doi: 10.1111/j.1438-8677.2012.00562.x


Poschet G, Hannich B, Raab S, Jungkunz I, Klemens, PAW, Krueger S, Neuhaus HE, Buettner M (2011) A novel Arabidopsis vacuolar glucose exporter is involved in cellular sugar homeostasis and affects composition of seed storage compounds. Plant Phys. 157, 1664-1676 doi: 10.1104/pp.111.186825

Wingenter K, Trentmann O, Winschuh I, Hörmiller I, Heyer A, Reinders J, Schulz A, Geiger D, Hedrich R, Neuhaus E (2011) A member of the mitogen-activated protein 3-kinase family is involved in the regulation of plant vacuolar glucose uptake. Plant J. 68, 890–900 doi: 10.1111/j.1365-313X.2011.04739.x

Cornelius S, Witz S, Rolletschek H, Möhlmann T (2011) Pyrimidine degradation influences germination seedling growth and production of Arabidopsis seeds. J. Exp. Bot. Bot. 62, 5623–5632 doi: 10.1093/jxb/err251

Schulz A, Beyhl D, Marten I, Wormit A, Neuhaus HE, Poschet G, Büttner M, Schneider S, Sauer N, Hedrich H (2011) Proton-driven sucrose symport and antiport is provided by the vacuolar transporters SUC4 and TMT1/2. Plant J. 68, 129-136 doi: 10.1111/j.1365-313X.2011.04672.x

Klaumann S, Nickolaus SD, Fürst SH, Starck S, Schneider S, Neuhaus HE, Trentmann O (2011) The tonoplast copper transporter COPt5 acts as an exporter and is required for inter-organ allocation of copper in Arabidopsis thaliana. New Phytologist 192, 393–404 doi: 10.1111/j.1469-8137.2011.03798.x
Highlighted by the Editor

Bernard C, Traub M, Kunz HH, Hach S, Trentmann O, Möhlmann T (2011) Equilibrative nucleoside transporter 1 (ENT1) is critical for pollen germination and vegetative growth in Arabidopsis. J. Exp. Bot. 62, 4627-4637 doi: 10.1093/jxb/err183

Haferkamp I, Fernie AR, Neuhaus HE (2011) Adenine-nucleotide transport in plants: much more than a mitochondrial issue. Trends in Plant Sci. 16, 507-515 doi: 10.1016/j.tplants.2011.04.001

Rieder B, Neuhaus HE (2011) Identification of an Arabidopsis plasma membrane located ATP transporter important for anther development. Plant Cell 23, 1932-1944 doi: 10.1105/tpc.111.084574

Khatri NK, Gocke D, Trentmann O, Neubauer P, Hoffman F (2011) Single-chain antibody fragment production in Pichia pastoris: Benefits of prolonged pre-induction glycerol feeding. Biotech. J. 6, 452–462 doi: 10.1002/biot.201000193

Gasber A, Klaumann S, Trentmann O, Trampczynska A, Clemens S, Schneider S, Sauer N, Feifer I, Bittner F, Mendel R, Neuhaus HE (2011) Identification of an Arabidopsis solute carrier critical for intracellular transport and inter-organ allocation of molybdate. Plant Biol. 13, 710-718 doi: 10.1111/j.1438-8677.2011.00448.x

Jung B, Hoffmann C, Möhlmann T (2011) Arabidopsis nucleoside hydrolases involed in intracellular and extracellular degradation of purines. Plant J. 65, 703-711 doi: 10.1111/j.1365-313X.2010.04455.x

Knab S, Mushak TM, Schmitz-Esser S, Horn M, Haferkamp I (2011) Nucleotide parasitism by Simkania negevensis (Chlamydiae). J. Bacteriol. 193, 225-235 doi: 10.1128/JB.00919-10

Muffler K, Leipold D, Scheller MC, Haas C, Steingroewer J, Bley T, Neuhaus HE, Mirata MA, Schrader J, Ulber R (2011) Biotransformation of triterpenes. Process Biochemistry 46, 1–15 doi: 10.1016/j.procbio.2010.07.015


Wingenter K, Schulz A, Wormit A, Wic S, Trentmann O, Hoermiller I, Heyer AG, Marten I, Hedrich R, Neuhaus HE (2010) Increased activity of the vacuolar monosaccharide transporter TMT1 alters cellular sugar partitioning, sugar signalling and seed yield in Arabidopsis. Plant Physiol. 154, 665-677 doi: 10.1104/pp.110.162040

Schmitz G, Reinhold T, Göbel C, Feussner I, Neuhaus HE, Conrath U (2010) Limitation of Nocturnal ATP import into chloroplasts seems to affect hormonal crosstalk, prime defense, and enhance disease resistance in Arabidopsis thaliana. Mol. Plant-Microbe Interact. 23, 1584–1591 doi: 10.1094/MPMI-02-10-0045

Möhlmann T, Bernard C, Hach S, Neuhaus HE (2010) Nucleoside transport and associated metabolism. Plant Biology 12, Supplement 1, 26-32 doi: 10.3389/fpls.2014.00443

Leipold D, Wünsch G, Schmidt M, Bart H-J, Bley T, Neuhaus HE, Bergmann H, Richling E, Muffler K, Ulber R (2010) Biosynthesis of ursolic acid derivatives by microbial metabolism of ursolic acid with Nocardia sp. strains - Proposal of new biosynthetic pathways. Process Biochemistry 45, 1043–1051 doi: 10.1016/j.procbio.2010.03.013

Jung-Il Cho, Burla, B, Lee D-W, Ryoo N, Hong, S-K, Kim H-B, Eom J-S, Choi S-B, Cho M-H, Bhoo S-H, Hahn T-R, Neuhaus HE, Martinoia E, Jeon, J-S (2010) Expression analysis and functional characterization of the monosaccharide transporters, OsTMTs, involving vacuolar sugar transport in rice (Oryza sativa). New Phytol. 186, 657–668 doi: 10.1111/j.1469-8137.2010.03194.x


Palmieri F, Rieder B, Ventrella A, Blanco E, Do PT, Nunes-Nesi A, Trauth U, Fiermonte G, Tjaden J, Agrimi G, Kirchberger S, Paradies E, Fernie AR, Neuhaus, HE (2009) Molecular identification and functional characterisation of Arabidopsis thaliana mitochondrial and chloroplastic NAD+ carrier proteins. J. Biol. Chem. 284, 31249-31259 doi: 10.1074/jbc.M109.041830
Supplemental Data

Gross R, Wolf MMN, Schumann C, Friedman N, Sheves M, Li L, Engelhard E, Trentmann O, Neuhaus HE, Diller R (2009) Primary photoinduced protein response in bacteriorhodopsin and sensory rhodopsin II. J. Am. Chem. Soc. 131, 14868–14878 doi: 10.1021/ja904218n

Jung B, Flörchinger M, Kunz H-H, Traub M, Wartenberg R, Jeblick W, Neuhaus HE, Möhlmann T (2009) Uridine-Ribohydrolase (URH) is a key regulator of uridine degradation. Plant Cell 21, 876–891 doi: 10.1105/tpc.108.062612
Highlighted by the Science Editor of Plant Cell

Ast M*, Gruber A*, Schmitz-Esser S, Neuhaus HE, Kroth P, Horn H, Haferkamp I (2009) Diatom plastids depend on nucleotide import from the cytosol. Proc. Natl. Acad. Sci. USA 106, 3621–3626 doi: 10.1073/pnas.0808862106
*both authors contributed equally to this paper

Herrmann JM, Kauff F, Neuhaus HE (2009) Thiol oxidation in bacteria, mitochondria and chloroplasts: Common principles but three unrelated machineries? Biochim. Biophys. Acta 1793, 71–77 doi: 10.1016/j.bbamcr.2008.05.001


Trentmann O, Jung B, Neuhaus HE, Haferkamp I (2008) Non-mitochondrial ATP/ADP transporters accept phosphate as third substrate. J. Biol. Chem. 283, 36486–36493 doi: 10.1074/jbc.M806903200

Linka N, Theodoulou FL, Haslam RP, Linka M, Napier NA, Neuhaus HE, Weber APM (2008) Peroxisomal ATP import is essential for seedling development in Arabidopsis thaliana. Plant Cell 20, 3241–3257 doi: 10.1105/tpc.108.062042
Highlighted by the Science Editor of Plant Cell

Deschamps P, Haferkamp I, d’Hulst C, Neuhaus HE, Ball SG (2008) The relocation of starch metabolism to chloroplasts: when, why and how. Trends in Plant Sci. 13, 574-582 doi: 10.1016/j.tplants.2008.08.009

Kirchberger S, Tjaden J, Neuhaus HE (2008) Characterization of the Arabidopsis Brittle1 transport protein and impact of reduced activity on plant metabolism. Plant J. 56, 51-63 doi: 10.1111/j.1365-313X.2008.03583.x

Leroch M*, Neuhaus HE*, Kirchberger S, Zimmermann S, Melzer M, Gerhold H, Tjaden J (2008) Identification of a novel adenine nucleotide transporter in the endoplasmic reticulum of higher plants. Plant Cell 20, 438–451 doi: 10.1105/tpc.107.057554
*both authors contributed equally to this paper
Highlighted by the News & Reviews Editor of Plant Cell

Zhang L, Häusler RE, Greiten C, Hajirezaei M-R, Haferkamp I, Neuhaus HE, Flügge U-I, Ludewig F (2008) Overriding the co-limiting import of carbon and energy into tuber amyloplasts increases the starch content and yield of transgenic potato plants. Plant Biotech. J. 6, 453–464 doi: 10.1111/j.1467-7652.2008.00332.x

Schmitz-Esser S, Haferkamp I, Knab S, Penz T, Ast M, Kohl C, Wagner M, Horn M. (2008) Lawsonia intracellularis contains a gene encoding a functional rickettsia-like ATP/ADP translocase for host exploitation. J. Bacteriol. 190, 5746-5752 doi: 10.1128/JB.00391-08

Williams BAP*, Haferkamp I*, Keeling PJ (2008) An ADP/ATP-specific mitochondrial carrier protein in the Microsporidian Antonospora locustae. J. Mol. Biol. 375, 1249-1257 doi: 10.1016/j.jmb.2007.11.005
*both authors contributed equally to this paper

Urbany C, Neuhaus HE (2008) Citrate uptake into Pectobacterium atrosepticum is critical for bacterial virulence. Mol. Plant-Microbe Interact. 21, 547–554 doi: 10.1094/MPMI-21-5-0547


Schmidt UG, Endler A, Schelbert S, Brunner A, Schnell M, Neuhaus HE, Marty-Mazars D, Marty F, Baginsky S, Martinoia E (2007) Novel tonoplast transporters identified using a proteomic approach with vacuoles isolated from cauliflower buds. Plant Physiol. 145, 216-229 doi: 10.1104/pp.107.096917

Trentmann O, Horn M, Terwisscha van Scheltinga, AC, Neuhaus HE, Haferkamp I (2007) Enlightening energy parasitism by analysis of an ATP/ADP transporter from Chlamydiae. PLoS Biol 5(9), e231. doi:10.1371/journal.pbio.0050231

Kirchberger S, Leroch M, Huynen MA, Wahl M, Neuhaus HE, Tjaden J (2007) Molecular and biochemical analysis of the plastidic ADP-glucose transporter (ZmBT1) from Zea mays. J. Biol. Chem. 282, 22481-22491 doi: 10.1074/jbc.M702484200

Neuhaus E (2007) Transport of primary metabolites across the plant vacuolar membrane. FEBS-Lett. 581, 2223–2226 doi: 10.1016/j.febslet.2007.02.003

Haferkamp I (2007) The diverse members of the mitochondrial carrier family in plants. FEBS-Lett. 581, 2375–2379 doi 10.1016/j.febslet.2007.02.020

Hackstein JH, Tjaden J, Koopman WJH, Huynen M (2007) Hydrogenosomes (and related organelles, either) are not the same. In Origin of Mitochondria and Hydrogenosomes, W.Martin and M.Müller, eds (Heidelberg: Springer-Verlag), pp. 135-159 doi: 10.1007/978-3-540-38502-8_7

Reinhold T, Alawady A, Grimm B, Beran K, Jahns P, Conrath U, Bauer J, Reiser J, Melzer M, Jeblick W, Neuhaus HE (2007) Limitation of nocturnal import of ATP into Arabidopsis chloroplasts leads to photooxidative damage. Plant Journal 50, 293–304 doi: 10.1111/j.1365-313X.2007.03049.x

Martinoia E, Maeshima M, Neuhaus HE (2007) Vacuolar transporters and their essential role in plant metabolism. J. Exp. Bot. 58, 83–102 doi: 10.1093/jxb/erl183

Traub M, Flörchinger M, Piecuch J, Kunz H-H, Weise-Steinmetz A, Deitmer JW, Neuhaus HE, Möhlmann T (2007) The fur1 (fluorouridine insensitive 1) mutant is defective in equilibrative nucleoside transporter 3 (ENT3), thus representing an important pyrimidine nucleoside uptake system in Arabidopsis thaliana. Plant Journal 49, 855–864 doi: 10.1111/j.1365-313X.2006.02998.x


Wormit A, Trentmann O, Feifer I, Lohr C, Tjaden J, Meyer S, Schmidt U, Martinoia E, Neuhaus HE (2006) Molecular identification and physiological characterization of a novel monosaccharide transporter from Arabidopsis involved in vacuolar sugar transport. Plant Cell 18, 3476-90 doi: 10.1105/tpc.106.047290
Highlighted by the News & Reviews Editor of Plant Cell

Haferkamp I, Schmitz-Esser S, Wagner M, Neigel N, Horn M, Neuhaus HE (2006) Tapping the nucleotide pool of the host: novel nucleotide carrier proteins of Protochlamydia amoebophila. Mol. Microbiol. 60, 1534-1545 doi: 10.1111/j.1365-2958.2006.05193.x

Haferkamp I, Deschamps P, Ast M, Jeblick W, Maier U, Ball S, Neuhaus HE (2006) Molecular and biochemical analysis of periplastidial starch metabolism in the cryptophyte Guillardia theta. Eukaryotic Cell 5, 964-971 doi: 10.1128/EC.00381-05

Deschamps P, Haferkamp I, Dauvillée D, Haebel S, Steup M, Búléon A, Putaux J-L, Colleoni C, D'Hulst C, Plancke C, Gould S, Maier U, Neuhaus HE, Ball S (2006) The nature of the periplastidal pathway of starch synthesis in the cryptophyte Guillardia theta. Eukaryotic Cell 5, 954-963 doi: 10.1128/EC.00380-05

Flörchinger M, Zimmermann M, Traub M, Neuhaus HE, Möhlmann T (2006) Adenosine stimulates anabolic metabolism in developing castor bean (Ricinus communis L.) cotyledons. Planta 223, 340-348 doi: 10.1007/s00425-005-0091-1

Colasante C, Alibu VP, Kirchberger S, Tjaden J, Clayton C, Voncken F (2006) Characterization and developmentally regulated localization of the mitochondrial carrier protein homologue MCP6 from Trypanosoma brucei. Eukaryotic Cell 5, 1194-1205 doi: 10.1128/EC.00096-06

Hackstein JH, Tjaden J, Huynen M (2006) Mitochondria, hydrogenosomes and mitosomes: products of evolutionary tinkering! Curr. Genet. 50, 225-245 doi: 0.1007/s00294-006-0088-8


Leroch M, Kirchberger S, Haferkamp I, Wahl M, Neuhaus HE, Tjaden J (2005) Identification and characterization of a novel plastidic adenine nucleotide uniporter from Solanum tuberosum. J. Biol. Chem. 280, 17992-18000 doi: 10.1074/jbc.M412462200

Holtum JAM, Smith JAC, Neuhaus HE (2005) Intracellular transport and pathways of carbon flow in plants with crassulacean acid metabolism. Funct. Plant Biol. 32, 429-449 doi: 10.1071/fp04189

Neuhaus HE, Häusler R, Sonnewald U (2005) No need to shift the paradigm on the metabolic pathway to transitory starch in leaves. Trends Plant Sci. 10, 154-156 doi: 10.1016/j.tplants.2005.02.002

Hurth MA, Suh SJ, Kretzschmar T, Geis T, Bregante M, Gambale F, Martinoia E, Neuhaus HE (2005) Impaired pH homeostasis in Arabidopsis, lacking the vacuolar dicarboxylate transporter and analysis of carboxylic acid transport across the tonoplast. Plant Physiol. 137, 901-910 doi: 10.1104/pp.104.058453


Haferkamp I, Schmitz-Esser S, Linka N, Urbany C, Collingro A, Wagner M, Neuhaus HE (2004) A candidate NAD+ transporter in an intracellular bacterial symbiont related to Chlamydiae. Nature 432, 622-625 doi: 10.1038/nature03131

Trentmann O, Khatri NK, Hoffmann F (2004) Reduced oxygen supply increases process stability and product yield with recombinant Pichia pastoris. Biotechnol. Process 20, 1766-1775 doi: 10.1021/bp049711h

Reiser J, Linka N, Lemke L, Jeblick W, Neuhaus HE (2004) Molecular physiological analysis of the two plastidic ATP/ADP transporters from Arabidopsis thaliana. Plant Physiol. 136, 3524-3536 doi: 10.1104/pp.104.049502

Clausen C, Ilkavets I, Thomson R, Philippar K, Vojta A, Möhlmann T, Neuhaus HE, Fulgosi, H, Soll J (2004) Intracellular localization of VDAC proteins in plants. Planta 220, 30-37 doi: 10.1007/s00425-004-1325-3

Wormit A, Traub M, Flörchinger M, Neuhaus HE, Möhlmann T (2004) Characterization of three novel members of the Arabidopsis thaliana equilibrative-nucleoside transporter (ENT) family. Biochem. J. 383, 19-26 doi: 10.1042/BJ20040389

Vigeolas H, Möhlmann T, Martini N, Neuhaus HE, Geigenberger P (2004) Embryo-specific reduction of ADP-glucose pyrophosphorylase leads to an inhibition of starch synthesis and a delay in oil accumulation in developing seeds of Brassica napus L.. Plant Physiol., 136, 2676-2686 doi: 10.1104/pp.104.046854

Daugherty RM, Linka N, Audia JP, Urbany C, Neuhaus HE, Winkler HH (2004) The nucleotide transporter of Caedibacter caryophilus exhibits an extended substrate spectrum compared to the analogous ATP/ADP translocase of Rickettsia prowazekii. J. Bacteriol. 186, 3262-3265 doi: 10.1128/jb.186.10.3262-3265.2004

Klaus D, Ohlrogge JB, Neuhaus HE, Dörmann P (2004) Increased fatty acid production in potato by engineering of acetyl-CoA carboxylase. Planta 219: 389-396 doi: 10.1007/s00425-004-1236-3

Schmitz-Esser S, Linka N, Collingro A, Beier CL, Neuhaus HE, Wagner M, Horn M (2004) ATP/ADP translocases: a common feature of obligate intracellular amoebal symbionts related to Chlamydiae and Rickettsiae. J. Bacteriol. 186, 683-691 doi: 10.1128/JB.186.3.683-691.2004

Tjaden J., Haferkamp I., Boxma B., Tielens A.G.M., Huynen M., Hackstein J.H.P. (2004) A divergent ADP/ATP carrier in the hydrogenosomes of Trichomonas gallinae argues for independent origin of these organelles. Mol. Microbiol. 51, 1439-1446 doi: 0.1111/j.1365-2958.2004.03918.x


Emmerlich V, Linka N, Reinhold T, Hurth MA, Traub M, Martionoia E, Neuhaus HE (2003) The plant homolog to the human sodium/dicarboxylic cotransporter is the vacuolar malate carrier. Proc. Natl. Acad. Sci. USA 100, doi: 11122-11126 10.1073/pnas.1832002100

Conrath U, Linke C, Jeblick W, Geigenberger P, Quick WP, Neuhaus HE (2003) Enhanced resistance to Phythophthora infestans and Alternaria solani in leaves and tubers, respectively, of potato plants with decreased activity of the plastidic ATP/ADP transporter. Planta 19, 75-83 doi: 10.1007/s00425-003-0974-y

Schwöppe C, Winkler HH, Neuhaus HE (2003) Connection of transport and sensing by UhpC, the sensor for external glucose-6-phosphate in Escherichia coli. Eur. J. Biochem. 270, 1450-1457 doi: 10.1046/j.1432-1033.2003.03507.x

Linka N, Hurka H, Lang BF, Burger G, Winkler HH, Stamme C, Urbany C, Seil I, Kusch J, Neuhaus HE (2003) Phylogenetic relationship of non-mitochondrial nucleotide transport proteins in bacteria and eukaryotes. Gene 306, 27-35 doi: 10.1016/s0378-1119(03)00429-3


Voncken F, Boxma B, Tjaden J, Akhmanova A, Huynen M, Verbek F, Tielens AGM, Haferkamp I, Neuhaus HE, Vogels G, Veenhuis M, Hackstein JHP (2002) Multiple origins of hydrogenosomes: functional and phylogenetic evidence from the ADP/ATP carrier of the anaerobic chytrid Neocallimastix sp. Mol. Microbiol. 44, 1441-1454 doi: 10.1046/j.1365-2958.2002.02959.x

Schwöppe C, Winkler HH, Neuhaus HE (2002) Properties of the glucose 6-phosphate transporter from Chlamydia pneumoniae (HPTcp) and the glucose 6-phosphate sensor from Escherichia coli (UhpC). J. Bacteriol. 184, 2108-2115 doi: 10.1128/jb.184.8.2108-2115.2002

Linke C, Conrath U, Jeblick W, Betsche T, Mahn A, Düring K, Neuhaus HE (2002) Inhibition of the plastidic ATP/ADP-transporter protein primes potato tubers for augmented elicitation of defense responses and enhances their resistance against Erwinia carotovora. Plant Physiol. 129, 1607-1615 doi: 10.1104/pp.000802

Haferkamp I, Hackstein JHP, Voncken F, Schmit G, Tjaden J (2002) Functional integration of mitochondrial and hydrogenosomal ADP/ATP carriers in the Escherichia coli membrane reveals different biochemical characteristics for plants, mammals and anaerobic chytrids. Eur. J. Biochem. 269, 3172-3181 doi: 10.1046/j.1432-1033.2002.02991.x


Möhlmann T, Mezher Z, Schwerdtfeger G, Neuhaus HE (2001) Characterization of a concentrative type of adenosine transporter from Arabidopsis thaliana (ENT1,At). FEBS Lett. 509, 370-374 doi: 10.1104/pp.105.060137

Geigenberger P, Stamme C, Tjaden J, Schulze A, Quick WP, Betsche T, Kersting HJ, Neuhaus HE (2001) Tuber physiology and properties of starch from tubers of transgenic potato plants with altered plastidic adenylate transporter activity. Plant Physiol. 125, 1667-1678 doi: 10.1104/pp.125.4.1667


Neuhaus HE, Emes MJ (2000) Nonphotosynthetic metabolism in plastids. Ann. Rev. Plant Physiol. Plant Mol. Biol. 51, 111-140 doi: 10.1146/annurev.arplant.51.1.111

Neuhaus HE, Wagner R (2000) Solute pores, ion channels, and metabolite transporters in the outer and inner envelope membranes of higher plant plastids. Biochim. Biophys. Acta 1465, 307-323 doi: 10.1016/S0005-2736(00)00146-2

Trentmann O, Decker C, Winkler HH, Neuhaus HE (2000) Charged amino-acid residues in transmembrane domains of the plastidic ATP/ADP transporter from Arabidopsis are important for transport efficiency, substrate specificity, and counter exchange properties. Eur. J. Biochem. 267, 4098-4105 doi: 10.1046/j.1432-1033.2000.01468.x

before 2000

Winkler HH, Neuhaus HE (1999) Non-mitochondrial atp transport. Trends in Plant Science 24, 64-68 Möhlmann T., Tjaden J. & Neuhaus H.E. (1999) Starch synthesis in plant storage tissues: precurser dependency and function of the plastidic ATP/ADP-transporter. Review In: Plant Carbohydrate Biochemistry. Bryant, J.A., Burrell, M.M. & Kruger, N.J. eds., pp. 255-267, BIOS Scientific Publishers, Oxford, UK. Full Text

Tjaden J, van der Laan M, Schwöppe C, Möhlmann T, Winkler HH, Neuhaus HE (1999) Two nucleotide transport proteins in Chlamydia trachomatis, one for net nucleoside triphosphate uptake and the other for the transport of energy. J. Bacteriol 181, 1196-1202 PMC93497

Möhlmann T, Tjaden J, Schwöppe C, Winkler HH, Kampfenkel K, Neuhaus HE (1998) Occurrence of two plastidic ATP/ADP transporters in Arabidopsis thaliana L. Molecular characterisation and comparative structural analysis of similar ATP/ADP translocators from plastids and Rickettsia prowazekii. Eur. J. Biochem. 252, 353-359 doi: 10.1046/j.1432-1327.1998.2520353.x

Thom E, Möhlmann T, Quick WP, Camara B, Neuhaus HE (1998) Sweet pepper plastids: enzymic equipment, characterisation of the oxidative pentose phosphate pathway, and transport of phosphorylated intermediates across the envelope membrane. Planta 204, 226-233 doi: 10.1007/s004250050251

Tjaden J, Schwöppe C, Möhlmann T, Neuhaus HE (1998) Expression of a plastidic ATP/ADP transporter gene in Escherichia coli leads to a functional adenine nucleotide transport system in the bacterial cytoplasmic membrane. J. Biol. Chem. 273, 9630-9636 doi: 10.1074/jbc.273.16.9630

Tjaden J, Möhlmann T, Kampfenkel K, Henrichs G, Neuhaus HE (1998) Altered plastidic ATP/ADP-transporter activity influences potato (Solanum tuberosum) tuber morphology, yield and composition of tuber starch. Plant J. 16, 531-540 doi: 10.1046/j.1365-313x.1998.00317.x

Emes MJ, Neuhaus HE (1997) Metabolism and transport in non-photosynthetic plastids. J. Exp. Bot. 48, 1995-2005 Full text 

Neuhaus HE, Thom E, Möhlmann T, Steup M, Kampfenkel K (1997) Characterization of a novel eukaryotic ATP/ADP translocator located in the plastid envelope of Arabidopsis thaliana L. Plant J. 11, 73-82 doi: 10.1046/j.1365-313x.1997.11010073.x

Quick WP, Neuhaus HE (1997) The regulation and control of photosynthetic carbon assimilation. In CH Foyer, ed A Molecular Approach to Primary Metabolism in Plants. Taylor & Francis, London, UK, pp 41-61 Full text 

Möhlmann T, Tjaden J, Henrichs G, Quick WP, Häusler R, Neuhaus HE (1997) ADP-glucose drives starch synthesis in isolated maize endosperm amyloplasts: characterization of starch synthesis and transport properties across the amyloplast envelope. Biochem. J. 324, 503-509 doi: 10.1042/bj3240503

Möhlmann T, Neuhaus HE (1997) Precursor and effector dependency of lipid synthesis in amyloplasts isolated from developing maize and wheat endosperm. J. Cereal Sci. 26, 161-167 doi.org/10.1006/jcrs.1997.0116

Quick WP, Neuhaus HE (1996) Evidende for two types of phosphate translocators in sweet-pepper (Capsicum annuum L.) fruit chromoplasts. Biochem. J. 320, 7-10 doi: 10.1042/bj3200007

Neuhaus HE, Schulte N (1996) Starch degradation in chloroplasts isolated from C3 or CAM (crassulacean acid metabolism)-induced Mesembryanthemum crystallinum L. Biochem. J. 318, 945-953 doi: 10.1042/bj3180945

Neuhaus HE, Maaß U (1996) Unidirectional transport of orthophosphate across the envelope of isolated cauliflower-bud amyloplasts. Planta 198, 542-548 doi: 10.1007/BF00262640

Batz O, Scheibe R, Neuhaus HE (1995) Purification of chloroplasts from fruits of green-pepper (Capsicum annuum L.) and characterization of starch synthesis. Evidence for a functional chloroplastic hexose-phosphate translocator. Planta 196, 50-57 doi: 10.1007/BF00193216

Quick WP, Scheibe R, Neuhaus HE (1995) Induction of hexose-phosphate translocator activity in spinach chloroplasts. Plant Physiol. 109, 113-121 doi:  10.1104/pp.109.1.113

Thom E, Neuhaus HE (1995) Oxidation of imported or endogenous carbohydrates by isolated chloroplasts from green pepper fruits. Plant Physiol. 109, 1421-1426 doi: 10.1104/pp.109.4.1421

Neuhaus HE, Henrichs G, Scheibe R (1995) Starch degradation in intact amyloplasts isolated from cauliflower buds (Brassica oleracea L.). Planta 195, 496-504 doi: 10.1007/BF00195706

Möhlmann T, Batz O, Maaß U, Neuhaus HE (1995) Analysis of carbohydrate transport across the envelope of isolated cauliflower-bud amyloplasts. Biochem. J. 307, 521-526 doi: 10.1042/bj3070521

Kampfenkel K, Möhlmann T, Batz O, van Montagu M, Inzé D, Neuhaus HE (1995) Molecular characterization of an Arabidopsis thaliana cDNA encoding a novel putative adenylate translocator of higher plants. FEBS Lett. 374, 351-355 doi: 10.1016/0014-5793(95)01143-3

Möhlmann T, Scheibe R, Neuhaus HE (1994) Interaction between fatty-acid and starch synthesis in isolated amyloplasts from cauliflower floral buds. Planta 194, 492-497 doi: 10.1007/BF00714461

Batz O, Maaß U, Henrichs G, Scheibe R, Neuhaus HE (1994) Glucose- and ADPGlc-dependent starch synthesis in isolated cauliflower-bud amyloplasts. Analysis of the interaction of various potential precursors. Biochim. Biophys. Acta 1200, 148-154 doi: 10.1016/0304-4165(94)90129-5

Kang X, Neuhaus HE, Scheibe R (1994) Subcellular localization of quinate: oxidoreductase from Phaseolus mungo L. sprouts. Z. Naturforsch. 49c, 415-420 doi: 10.1515/znc-1994-7-805

Neuhaus HE, Henrichs G, Scheibe R (1993) Characterization of glucose-6-phosphate incorporation into starch by isolated intact cauliflower-bud plastids. Plant Physiol. 101, 573-578 doi: 10.1104/pp.101.2.573

Batz O, Scheibe R, Neuhaus HE (1993) Identification of the putative hexose-phosphate translocator of amyloplasts from cauliflower buds. Biochem. J. 294, 15-17 doi: 10.1042/bj2940015

Neuhaus HE, Batz O, Thom E, Scheibe R (1993) Purification of highly intact plastids from various heterotrophic plant tissues: analysis of enzymic equipment and precursor dependency for starch biosynthesis. Biochem. J. 296, 395-401 doi: 10.1042/bj2960395

Batz O, Scheibe R, Neuhaus HE (1992) Transport processes and corresponding changes in metabolite levels in relation to starch synthesis in barley (Hordeum vulgare L.) etioplasts. Plant Physiol. 100, 184-190 doi: 10.1104/pp.100.1.184

Neuhaus HE, Stitt M (1991) Inhibition of photosynthetic sucrose synthesis by imidodiphosphate, an analog of inorganic pyrophosphate. Plant Sci. 76, 49-55 doi: 10.1016/0168-9452(91)90217-V

Neuhaus HE, Stitt M (1990) Control analysis of photosynthate partitioning. Impact of reduced activity of ADP-glucose pyrophosphorylase or plastid phosphoglucomutase on the fluxes to starch and sucrose in Arabidopsis thaliana (L.) Henyh. Planta 182, 445-454 doi: 10.1007/BF02411398

Schulze W, Stitt M, Schulze ED, Neuhaus HE, Fichtner K (1990) A quantification of the significance of assimilatory starch for growth of Arabidopsis thaliana L. Heynh. Plant Physiol. 95, 890-895 doi: 10.1104/pp.95.3.890

Neuhaus HE, Krause K-P, Stitt M (1990) Comparison of pyrophosphate turnover and the maximum catalytic activity of pyrophosphate: fructose-6-phosphate phosphotransferase in leaves. Phytochem. 29, 3411-3415 doi: 10.1016/0031-9422(90)85248-E

Smith AM, Neuhaus HE, Stitt M (1990) The impact of decreased activity of starch-branching enzyme on photosynthetic starch synthesis in leaves of wrinkled-seeded peas. Planta 181, 310-315 doi: 10.1007/BF00195881

Dancer JE, Neuhaus HE, Stitt M (1990) Subcellular compartmentation of uridine nucleotides and nucleoside-5'-diphosphate kinase in leaves. Plant Physiol. 92, 637-641 doi: 10.1104/pp.92.3.637

Neuhaus HE, Quick WP, Siegl G, Stitt M (1990) Control of photosynthate partitioning in spinach leaves: Analysis of the interaction between feedforward and feedback regulation of sucrose synthesis. Planta 181, 583-592 doi: 10.1007/BF00193014

Neuhaus HE, Kruckeberg AL, Feil R, Stitt M (1989) Reduced activity mutants of phosphoglucose isomerase in the cytosol and chloroplast of Clarkia xantiana. I. Planta 178, 110-122 doi: 10.1007/BF00392534

Quick WP, Siegl G, Neuhaus HE, Feil R, Stitt M (1989) Short-term water stress leads to a stimulation of sucrose synthesis by activating sucrose-phosphate synthase. Planta 177, 535-546 doi: 10.1007/BF00392622

Quick WP, Neuhaus HE, Feil R, Stitt M (1989) Fluoride leads to an increase of inorganic pyrophosphate and an inhibition of photosynthetic sucrose synthesis in spinach leaves. Biochim. Biophys. Acta 973, 263-271 Full Text

Kruckeberg AL, Neuhaus HE, Feil R, Gottlieb LD, Stitt M (1989) Decreased-activity mutants of phosphoglucose isomerase in the cytosol and chloroplasts of Clarkia xantiana. Biochem. J. 261, 457-467 doi: 10.1042/bj2610457

Neuhaus HE, Stitt M (1989) Perturbation of photosynthesis in spinach leaf discs by low concentrations of methyl viologen. Planta 179, 51-60 doi: 10.1007/BF00395770

Neuhaus HE, Holtum JAM, Latzko E (1988) Transport of phosphoenolpyruvate by chloroplasts from Mesembryanthemum crystallium L. exhibiting crassulacean acid metabolism. Plant Physiol. 87, 64-68 doi: 10.1104/pp.87.1.64

Leegood RC, Labate C, Huber SC, Neuhaus HE (1988) Phosphate sequestration by glycerol and its effect on photosynthetic carbon assimilation by leaves. Planta 176, 117-126 doi: 10.1007/BF00392487

Holtum JAM, Fahrendorf T, Neuhaus HE, Mukherjee U, Latzko E (1986) Carbohydrate storage strategy, F-2,6-P2, and CAM. In J Biggins, ed Progress in Photosynthesis Research. Martinus Nijhoff, Dordrecht, pp 10.735-10.738 Full Text

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